脑性瘫痪儿童56例生长发育状况分析

Analysis. of the growth and development condition in 56 children with cerebral palsy

目的分析脑性瘫痪儿童的生长发育状况，探讨青春期发育对脑瘫儿童成年身高的影响。方法选择56例脑性瘫痪儿童作为研究对象，同期健康体检儿童34例作为对照，测量身高、体质量，检查性征发育情况，计算身高和体质量标准差、身高年龄、骨龄、预测成年身高、靶身高，并进行统计学分析。结果脑性瘫痪组患儿身高标准差为（-1．29±1．39），体质量标准差为（-0．77±1．20），低于对照组的（0．40±0．95）和（0．38±1．01）（t=-6．270、-4．676，均P〈0．05）。青春前期脑瘫组患儿生活年龄大于身高年龄和骨龄，差异均有统计学意义（t=6．381、7．939，均P〈0．05），身高年龄和骨龄差异无统计学意义（P〉0．05），预测成年身高和靶身高差异无统计学意义（P〉0．05）。青春期脑瘫组患儿生活年龄和骨龄大于身高年龄，差异均有统计学意义（t=3．438、-3．759，均P〈0．05），生活年龄和骨龄差异无统计学意义（P〉0．05），预测成年身高低于靶身高，差异有统计学意义（t=-5．204，P〈0．05）。结论脑性瘫痪儿童生长发育落后，青春期发育的启动年龄和过程与正常儿童相似，青春期发育后骨龄增长加速，预测成年身高明显落后于靶身高。

Objective To analyze the growth and development condition of the children with cerebral palsy, and to investigate the influence of puberty on their adult height. Methods 56 children with cerebral palsy were se- lected as research subjects. 34 healthy children were selected as control group. Their height and weight were meas- ured,the development condition of their sexual character was checked, and then standard deviation of height and weight, height age and bone age were calculated, adult height and target height were predicted and analyzed. Results The standard deviation of height and weight in cerebral palsy group was （ - 1.29 ±1.39） and （ - 0.77 ±1.20） respectively,which was lower than that of the normal control group [ （0.40 ± 0.95 ）, （0.38±1.01 ） ] （ t = - 6.270 , - 4.6 7 6 , all P 〈 0.0 5 ） . In preadolescent cerebral palsy group, the chronobiological age was bigger than their height age and bone age, the difference was significam （ t = 6. 381,7. 939, all P 〈 0.05 ）, but there was no significant difference between height age and bone age （ P 〉 0.05）, there existed no significant difference between predicted adult height and target height（P〉 0.05 ）. In adolescent cerebral palsy group, the chronobiological age and bone age were larger than their height age ,which indicated significant difference（ t = 3. 438, - 3,759, all P 〈 0.05 ）, but there was no significant difference between the chronobiological age and bone age （ P 〉 0.05 ）, the predicted adult height was lower than target height, the difference was significant （ t = - 5. 204, P 〈 0.05 ）. Conclusion The growth and development of children with cerebral palsy would usually fall behind the normal children, but showed similarity in terms of starting age＇and process of puberty. After puberty, their bone age would increase dramatically, their predicted adult height would fall behind target height distinctly.