摘要
目的探讨脓毒症患者血清甲状腺激素水平变化后预后关系。方法对117例脓毒症患者总T3(total T3,TT3)、游离T3(free T3,FT3),总T4(total T4,TT4)、游离T4(free T4,rT4),垂体促甲状腺激素(thyroid-stimulating hormone,TSH)浓度水平与APACHEⅡ评分和死亡病例的相关性进行分析。结果脓毒症患者血清TT3、FT3、TT4、FT4均低于正常值,APACHEⅡ≤19分组与APACHEⅡ≥20分组比差异有统计学意义(P<0.05),死亡组与生存组比差异有统计学意义(P<0.05),TSH无明显改变。结论脓毒症患者血清甲状腺减激素水平与脓毒症病情危重程度呈负相关,病情越严重,血清TT3、FT3、TT4、FT4越低,死亡风险越大,可以作为脓毒症患者预后的临床参考指标。
Objective Ananoss of exploring sepsis in patiente with thyroid homone levels. Methods 117 cases of sepsis in patients with total T3（total T3, TT3）free T3（free of T3 and FT3）,total T4（total T4 in RT4）,pituitary thyroid stimulating homone（thyroid-stimulating homone of TSH）levels with APACHE II score and the deaths of the correlation analysis. Results Patients with sepsis serum TT3 and FT3, TT4, FT4 were lower then normal values of APACHE If ≤ 19 group of APACHE II≥20 group than the difference was statiatfically significant （P〈0.05）, the death group and survival group than in the difference was statistically significant（P〈0.05）, TSH no significant change. Conclusion Sepsis in patients with serum thgroid less hormone levels with sepsis severity of illness was negatively correlated with the more serious the illness,the serum of TT3 and FT3, TT4 and FT4 lower as a clinical reference of the prognosis of patients with sepsis indicators.
出处
《中国医药指南》
2013年第16期435-437,共3页
Guide of China Medicine
