613株病原菌分布及其主要耐药情况分析

Distribution of 613 Strains of Pathogenic Bacteria and Antibiotic Resistance of the Main Pathogenic Bacteria analysis

目的分析故城县医院检出的病原菌分布及其主要病原菌的耐药情况,为临床合理用药和控制医院感染提供参考。方法采用恒星细菌分析系统对2012年6月至2012年12月分离的613株病原菌进行鉴定,药敏试验采用琼脂纸片扩散法。结果 2012年下半年共收集非重复临床分离菌株613株,其中革兰阴性菌417株占68%,革兰阳性菌128株占20.8%,真菌68株占11.2%,除真菌外其他病原菌的耐药率较之上半年都明显增加。结论应完善抗菌药物的规范使用,加强细菌培养意识,严格控制医院感染病例的诊断和用药标准,预防抗菌药物耐药率的快速产生。革兰阴性杆菌在住院患者感染中占主要地位,临床医师应警惕革兰阴性菌引起的感染。

Objective To analyze the distribution of pathogenic bacteria isolated from our hospital and the antibiotic resistance of the main pathogenic bacteria ,to provide a basis for clinical rational drug use and control the hospital infection .Methods 613 strains of pathogenic bacteria separated from patients in our hospital during June to December of 2012 were identifited by Hengxing bacteria analysis and detected the antibiotic resistance by Kirby-Bauer（K-B） agar tapediffusion. Results We gather 613 strains in last year of 2012,there were 417 strains Gram-negative bacteria （68%）,128 strains Gram-positive bacteria（20.8%）,and 68 strains fungi（13.2%）, obviously the antibiotic resistance of pathogenic bacteria was higer than first half year.Conclusion It is necessary to reasonably use antibiotics,strengthen the awareness of bacteria culture and strictly comply the standards of diagnosis and antibiotic use so as to prevent the antibiotic resistanc of pathogenic bacteria. Gram-negative bacteria was the main pathogenic bacteria,clinician should ware the infection of Gram-negative bacteria.