血管性痴呆患者炎性因子的检测及意义

Inspection and Significance of Inflammatory Factors of Patients with Vascular Dementia

目的了解炎性因子与血管性痴呆的关系。方法采用回顾性研究方法从我院门诊及住院患者中收集34名血管性痴呆(vasculardementia,VaD)患者检测他们血液中的炎性因子,并从体检中心随机抽取相匹配的正常人与之对照,比较两组间炎性因子浓度。结果 VaD组血清IL-6及TNF-α浓度与正常人组相比显著性增高,差异具有统计学意义(P<0.05)。结论炎性因子可能参与了VaD的发病过程。

Objective Understand the relationship between inflammatory cytokines and vascular dementia. Methods Collected 34 hospital inpatients and outpatients with vascular dementia（VaD） and 30 Matched healthy subjects,detect their inflammatory cytokines in their blood. Results serum IL-6 and TNF-α concentration of VaD group is significantly higher than normal group, the difference was statistically significant （P〈0.05）.Condusion Inflammatory factors may be involved in the pathogenesis of VaD.