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多西他赛联合奥沙利铂治疗老年晚期胃癌的临床观察

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摘要 目的观察多西他赛联合奥沙利铂治疗老年晚期胃癌的近期疗效和和副反应。方法 43例老年晚期胃癌患者,采用多西他赛30mg/m2静脉滴注d1,8;奥沙利铂130mg/m2静脉滴注d2,21d为1个周期。2周期后评定疗效。结果 43例患者均可评价疗效,其中2例完全缓解(CR),20例部分缓解(PR),11例稳定(SD),10例进展(PD),总有效率(CR+PR)53.49%,临床受益率(CR+PR+SD)76.74%。中位疾病至进展时间(TTP)6.5个月(3.6~11.7个月),中位总生存(OS)为11.6个月(5.8~14.7个月)。结论多西他赛联合奥沙利铂治疗晚期胃癌效果较好、副作用较低,是一种治疗老年晚期胃癌安全有效的方法。
出处 《中国医药指南》 2013年第16期510-511,共2页 Guide of China Medicine
基金 河南省科技厅重点科技攻关资金资助(112102310257)
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