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The preparation of a novel polydopamine-graft-poly(2-methyl-2-oxazoline) protein-resistant coating and its applications in protein separation

The preparation of a novel polydopamine-graft-poly(2-methyl-2-oxazoline) protein-resistant coating and its applications in protein separation
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摘要 A novel polydopamine-graft-poly(2-methyl-2-oxazoline) (PDA-g-PMOXA) coating was prepared by immobilizing poly(2-methyl-2-oxazoline) (PMOXA) onto material surfaces through polydopamine (PDA) anchored coating for the first time. And then, the chemical composition, hydrophilicity, and protein-resistant properties of the PDA-g-PMOXA coating were studied using X-ray photoelectron spectroscopy (XPS), contact angel (CA) test, surface plasmon resonance (SPR), and quartz crystal microbalance with dissipation (QCM-D) measurement. Finally, the coating was applied to the capillary inner surface for protein separation by capillary electrophoresis (CE). A novel polydopamine-graft-poly(2-methyl-2-oxazoline) (PDA-g-PMOXA) coating was prepared by immobilizing poly(2-methyl-2-oxazoline) (PMOXA) onto material surfaces through polydopamine (PDA) anchored coating for the first time. And then, the chemical composition, hydrophilicity, and protein-resistant properties of the PDA-g-PMOXA coating were studied using X-ray photoelectron spectroscopy (XPS), contact angel (CA) test, surface plasmon resonance (SPR), and quartz crystal microbalance with dissipation (QCM-D) measurement. Finally, the coating was applied to the capillary inner surface for protein separation by capillary electrophoresis (CE).
出处 《Chinese Chemical Letters》 SCIE CAS CSCD 2013年第7期597-600,共4页 中国化学快报(英文版)
基金 support of the Ministry of Science and Technology of China(No.2012CB933802)
关键词 PDA-g-PMOXA coating Protein-resistant properties Protein separation PDA-g-PMOXA coating Protein-resistant properties Protein separation
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