放射作业医务人员血常规及淋巴细胞微核率检测结果分析

Analysis on detection results of PFLMNF and routine blood of medical staff exposed to radiation.

目的探讨接触医用射线工作人员血常规及淋巴细胞微核率的变化规律,为放射工作人员的健康监护和管理提供理论依据。方法对某医院73例放射作业人员进行血常规及淋巴细胞微核率检测,并与22例对照进行比较,分析工作岗位及工龄对血常规及淋巴细胞微核率的影响。结果接触医用射线组淋巴细胞微核异常率(42.47%)高于对照组(13.64%),差异有统计学意义(P<0.05),而且淋巴细胞微核率与工龄正相关(P<0.05,r=0.28)。血常规异常率(20.55%)与对照组(18.18%)相比,差异无统计学意义。不同工作岗位的年有效吸收剂量均低于职业照射剂量限值,其中年有效吸收剂量最高的介入放射组与最低的诊断放射组比较,差异有统计学意义(P<0.05),但2组的淋巴细胞微核率及血常规异常率差异无统计学意义。结论接触医用射线工作人员淋巴细胞微核率增高,与工龄正相关,与年有效吸收剂量无剂量效应关系。

Objective To explore the changing rule of PFLMNF and routine blood of medical staff exposed to radiation, so as to provide theoretical basis for health monitoring and management of the medical staff. Methods The blood cells and lymphocyte micronucleus collected from 73 medical workers exposed to radiation were tested, as well as compared with the 22 control group. The effects of operating post and seniority on routine blood and PFLMNF were also analyzed. Results The abnormal PFLMNF of group exposed to radiation （42.47%） was significantly higher than that of control groups （ 13.64% ） . The differences had statistical significance （P 〈 0.05） and there was positive correlation between PFLMNF and seniority （P 〈 0. 05, r = 0. 28 ） . Compared with the control group （ 18. 18% ）, there was no statistical significant difference of routine blood in the radiation group （20. 55% ） . The annual effective absorbed dose of different posts was lower than occupational exposure dose threshold. However there was no significant difference （P 〈 0. 05 ） in results of routine blood test between radiation group and control group. But there was no significant difference in results of PFLMNF and routine blood test between two groups. Conclusions The raise of PFLMNF of medical workers exposed to occupational radiation may be positively related with seniority, but had no dose - effect relationship with annual effective absorbed dose.