健脾利湿退黄法改善肿瘤晚期合并黄疸症状系统综述

The Spleen Dampness Jaundice Method In Improving Advanced Tumors Complicated With Jaundice Symptoms Evaluation System

[主要目的]分析健脾利湿退黄法改善肿瘤晚期合并黄疸症状临床资料。[资料来源]在辽宁中医药大学附属第一医院病案室,选取2011年3月至2012年9月辽宁中医药大学附属第一医院肿瘤科恶性肿瘤合并黄疸住院患者原始病历。[选择文献量及依据]①研究类型:临床观察。②研究对象:病理组织学/细胞学/影像学及肝功能化验,诊断为恶性肿瘤合并黄疸;均应用健脾利湿退黄法。③评价指标:KPS评分,症候评分。共37例住院恶性肿瘤合并黄疸患者原始病历。[数据提炼规则及应用方法]症状体征(身目发黄、上腹胀痛、食少纳呆、消瘦、睡眠欠佳、倦怠乏力、尿黄赤、口干而苦、恶心呕吐、发热、大便色白、腹泻、大便干结、反酸、腰痛、头晕、皮肤瘙痒),以症状体征出现频次排序。采用MicrosoftExce 2013软件建立数据库进行统计分析,以证候出现频次排序。体力状况评分参照kps评分标准,根据症候改善积分判断疗效价值。[数据综合得出结果与结论]肿瘤晚期合并黄疸临床症状出现频率依次为身目发黄、上腹胀痛、食少纳呆、消瘦、睡眠欠佳、倦怠乏力、尿黄赤、口干而苦、恶心呕吐、发热、大便色白、腹泻、大便干结、反酸、腰痛、头晕、皮肤瘙痒。阳黄(湿重于热型)有效率70.00%,阴黄(脾虚湿滞型)有效率72.70%,治疗效果优于其他证型。KPS提高稳定率为86.50%。健脾利湿退黄法在改善肿瘤晚期合并黄疸患者临床症状及提高生存质量效果显著。[未来展望]规范辩证分型及疗效判定标准制定,开展作用机理研究,中西医优势互补。

[Objective]The main clinical data of The Spleen Dampness Jaundice method improve the advanced cancer complicated with jaundice symptoms.[Source]In the First Affiliated Hospital of Liaoning University of Traditional Chinese Medicine,First Affiliated Hospital in 2011 March to 2012 September Liaoning University of Traditional Chinese Medicine cancer malignant tumor complicated with jaundice patients primitive case.[Select documents and evidence]①Research type： retrospective analysis.②The object of study： according to ＂ Chinese Medicine Department of internal medicine with the first diagnosis＂.The pathology or cytology or imaging examination and liver function tests confirmed,diagnosed with a malignant tumor complicated with jaundice;both the application of The Spleen Dampness Jaundice method treatment method.③The evaluation index： KPS score,symptom score.A total of 37 cases of malignant tumors in patients with jaundice original medical records.[Data extraction rules and method of application]Signs and symptoms（yellowing of the body and eyes,abdominal pain,eating less poor appetite,weight loss,poor sleep,fatigue,brownish red,dry and bitter,nausea and vomiting,fever,diarrhea,stool color white,dry stool,acid regurgitation,back pain,dizziness,skin itching）,to symptom frequency arrangement.Using Microsoft Excel 2013 software to establish database for statistical analysis,with syndrome frequency arrangement.The physical status score according to KPS score before and after treatment,according to the symptoms to improve the integral judge curative effect value.[Data synthesis results and conclusion]Cancer complicated with jaundice clinical symptoms of yellow body and eyes,abdominal pain,eating less poor appetite,weight loss,poor sleep,fatigue,brownish red,dry and bitter,nausea and vomiting,fever,diarrhea,stool color white,dry stool,acid regurgitation,back pain,dizziness,skin itching symptoms frequency sequence.Yang Huang（wet weight in thermal） efficiency 70%,Yin Huang（spleen deficiency and dampness stagnation） efficiency of 72.70%,better than other syndromes curative effect.To improve the stability of KPS was 86.50%.The Spleen Dampness Jaundice method in improving the clinical symptoms of patients with advanced cancer complicated with jaundice and improve the effect of quality of life significantly.[Future]Specification dialectical typing and efficacy criteria,research on the action mechanism of traditional Chinese medicine and Western medicine,complementary advantages,is the future direction of research in this field.