10种常用中药注射剂输液配伍后的稳定性研究

Research on Stability of Ten Commonly Traditional Chinese Medicine Injections Compatibility

目的通过实验观察10种常用中药注射剂与常用输液配伍后不同时间段内的稳定性,管理临床护士配药及液体的输注。方法观察10种中药注射剂与输液配伍后的药品外观,并考察其在0-4h内的性状、pH值、微粒数及吸光度。结果 10种常用中药注射剂注射液4 h内溶液澄明,未见沉淀生成及变色,pH值在正常范围内略有变化,不溶性微粒未发生,吸光度与0h比较略有变化,但均在可接受的正常范围内。结论 10种常用中药注射剂注射液在正常情况下可在4 h内输入人体,配液后1-2h内配伍使用最为稳定。

Objectve through a period of stability test of ten commonly used in traditional Chinese medicine injections and infusions compatibility, management clinical nurse dispensing and fluid infusion, Method observe the appearance of ten kinds of Chinese medicine injections and transfusion compatibility and investigated traits within 0 - 4h, PH value, the number of particles and the absorbance. Results ten kinds of traditional Chinese medicine injection injection solution within 4 h of clarity, no precipitate and discoloration, a slight change in the pH value is within the normal range, and insoluble particles did not occur, a slight change in absorbance Oh, but are within the acceptable within the normal range. Conclusion：The injection of 10 kinds of traditional Chinese medicine injection in normal circumstances within 4 h, enter the human body, the most stable with liquid compatible use within 1 - 2h.