健脾清肠法治疗127例轻中度活动期溃疡性结肠炎疗效的回顾性分析

Retrospective Analysis of Efficacy in Treatment of 127 Cases of Bowel and Spleen with Mild to Moderate Active Ulcerative Colitis

目的:回顾研究近10年中药健脾清肠法治疗轻中度活动期溃疡性结肠炎的疗效及组方规律。方法:收集127例2000年1月～2011年3月在上海中医药大学附属龙华医院单纯使用中药健脾清肠法治疗的轻中度活动期溃疡性结肠炎(UC)患者,观察治疗前后中医证候变化及结肠镜检查的改变,中药起效时间,并总结健脾清肠法的组方规律。结果:单纯使用健脾清肠法治疗的轻中度活动期UC患者的总有效率为91.30%。其对改善UC患者中医证候有显著疗效,尤其对粘液脓血便症状改善最为明显(P<0.01)。中药起效时间在2.72±1.03 w。其中31例近期复查肠镜的UC患者,结肠镜改善有显著疗效。结论:健脾清肠法治疗轻中度活动期溃疡性结肠炎脾虚湿热证疗效确切。

Objective： Retrospective study of patients with ulcerative colitis in recent 10 years,focus on observation of spleen and bowel treatment with traditional Chinese medicine in active treatment of mild to moderate ulcerative colitis.Methods： A retrospective study of the subject methods with statistics taken nearly 10 years（2000.1-2011.3） in Shanghai Longhua hospital of traditional Chinese medicine,of which 127 cases are using simple spleen and bowel treatment with traditional Chinese medicine to treat mild to moderate active UC patients,observe syndrome changes before and after treatment as well as changes in colonoscopy,medicine onset time.Summary spleen bowel law rule set of square.Results： 127 cases are using the spleen and intestines treatment with traditional Chinese medicine only with mild to moderate active UC,the total effective rate is 91.30% of total UC patients.Significant improvement in patients with UC and its efficacy syndromes had a significant effect change.In particular,blood and pus on mucous most obvious symptom improvement（P 0.01）.Onset time with traditional Chinese medicine is 2.72 ± 1.03 weeks.The recent review of results of 31 cases of colonoscopy in UC patients showed improvement.Conclusion： The spleen and bowel treatment to treat mild to moderate active ulcerative colitis is effective.