无创正压通气治疗慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭的临床效果观察

目的对无创正压通气(NIPPV)治疗慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭的临床疗效进行研究。方法选择2009年8月-2012年10月收治的100例慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭患者,随机分为试验组(50例)进行NIPPV治疗,对照组(50例)进行常规治疗。结果两组患者的氧分压(PaO2)、二氧化碳分压(PaCO2)、血氧饱和度(SpO2)、心率(HR)、呼吸(RR)差异均有统计学意义(P<O.05),试验组患者的血气分析结果显著好于对照组。结论无创正压通气治疗慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭可改善患者预后,降低气管插管率,减少并发症的发生,安全性较好。

Objective To observe and study the clinical efficacy of noninvasive positive pressure ventilation （NIPPV）in the treatment of chronic obstructive pulmonary disease with respiratory failure. Methods To select the 50 patients in department from August 2009 to October 2012 with chronic obstructive pulmonary disease combined with type 1I respiratory failure as experimental group to get the treatment of NIPPV.Also select 50 cases as the control group treated with conventional treatment. Results The patients of two groups were significantly different in partial pressure of oxygen （PaO 2）, partial pressure of carbon dioxide （PaCO 2）, oxygen saturation of blood （SpO 2）, cardiac rate （HR）, breathing rate（RR）（P〈0.05）. The blood gas analysis results of experimental group patients were significantly better than those of the control group. Conclusion The treatment of noninvasive positive pressure ventilation in the treatment of chronic obstructive pulmonary disease complicated by respiratory failure could improved patient outcomes, reduce the rate of endotrachea 1 intubation and reduce the incidence of complications. It had good security.