期刊文献+

胺碘酮对老年室性心律失常治疗效果的观察 被引量:4

下载PDF
导出
摘要 目的探讨胺碘酮治疗老年室性心律失常的临床疗效。方法选取近年来诊治的老年室性心律失常患者194例作为研究对象。将患者随机分为观察组和对照组各97例,对照组患者采用常规综合方法进行治疗,观察组患者在对照组基础上采用胺碘酮进行治疗,对两组患者的疗效及用药安全性进行评价分析。结果观察组患者治疗后疗效显著,总有效率达90.7%,优于对照组患者的80.4%,差异具有统计学意义(P<0.05)。结论在常规综合治疗基础上采用胺碘酮对老年室性心律失常患者进行治疗效果良好,能够在保证用药安全的情况下改善患者心律失常症状。
作者 周志堂
出处 《当代医学》 2013年第21期144-145,共2页 Contemporary Medicine
  • 相关文献

参考文献4

二级参考文献20

  • 1郭继鸿.胺碘酮的现代观点(续)[J].临床心电学杂志,2007,16(3):215-226. 被引量:21
  • 2dos Santos Filho HO, Ilha JO, Silva LC, et al. Comparative bioavailability study with two amiodarone tablet formulations administered with and without food in healthy subjects [ J ]. Arzneimittelforschung,2007,57:582.
  • 3Meng X, Mojaverian P, Doedee M, et al. Bioavailability of amiodarone tablets administered with and without food in healthy subjects [J]. Am J Cardiol, 2001,87:432.
  • 4Fukuchi H,Nakashima M,Araki R. Effect of obesity on serum amiodarone concentration in Japanese patients: population pharmacokinetic investigation by multiple trough screen analysis [ J ]. J Clinical Pharmacy and Therapeutics ,2008,33 : 1.
  • 5Anastasiou-Nana MI, Nanas JN, Alexopoulos G. Amiodamne concentration in human myoeardium after rapid intravenous administration[J]. Cardiovase Drags Ther,1999,13:265.
  • 6Connolly SJ. Evidence-based analysis of amiodarone efficacy and safety [ J ]. Circulation, 1999,100:2 025.
  • 7Vorperian VR, Havighurst TC, Miller S, et al. Adverse effects of low dose amiodarone a meta-analysis[ J]. J Am Coll Cardiol, 1997, 30:791.
  • 8Liu DW,Antzelevitch C. Characteristics of the delayed rectifier current ( Ikr and Iks ) in canine ventricular epicardial, midmyocardial, and endocardial myocytes : a weaker Iks contributes to the longer action potential of the M cell [ J ]. Circulation Research, 1995,76 : 351.
  • 9Shi GF, Xu W, Huang SS. Mechanism of the delayed onset of action after intravenous amiodarone for treatment of ventricular arrhythmias[ J]. Drug Development Research, 2003, 58 : 145.
  • 10Kowey PR, Levine JH, Herre JM,et al. Randomized, double-blind comparison of intravenous amiodarone and bretylium in the treatment of patients with recurrent, hemodynaroically destabilizing ventricular tachycardia or fibrillation. The Intravenous Amiodarone Multicenter Investigators Group[ J]. Circulation, 1995,92:3 255.

同被引文献28

  • 1阿曼古力.艾麦提,阿依孜木古力.吐尔孙.口服胺碘酮治疗心房纤颤临床分析(附32例报告)[J].中国医药指南,2008,6(20):101-102. 被引量:2
  • 2原海燕,罗佳,王峰,李焕德.小剂量胺碘酮治疗老年心律失常的临床研究[J].中国医院药学杂志,2005,25(4):304-306. 被引量:4
  • 3Gao Y ,Zhang P, Liang X. Effects of low-dose amiodarone and Betaloc on the treatment of hypertrophic cardiomyopathy complicated with malignantventrieular arrhythmias[J]. Pak J Med Sei ,2014,30(2) :291-294.
  • 4中华医学会心血管病学分会,中国生物医学工程学会心律分会.胺碘酮抗心律失常治疗应用指南工作组.胺碘酮抗心律失常治疗应用指南(2008)[EB/OL].[2015-10-25]http://www.360doc.corn/content/13/0505/1113006878_283083351.shtml.
  • 5Piccini JP,A1-Khatib SM ,Wojdyla DM ,et al. Comparison of safety of so- talol versus amiodarone in patients with atrial fibrillation and coronary artery disease[J]. Am J Cardio1,2014,114(5 ) : 716-722.
  • 6Joukar S ,Zarisfi Z ,Sepehri G,et al. Efficacy of Melissa officinalis in sup- pressing ventricular arrhythmias following ischemia-reperfusion of the heart :a comparison with amiodarone[J]. Med Princ Pract, 2014,23 (4): 340-345.
  • 7Gali WL,Sarabanda AV, Baggio JM, et al. Implantable cardioverter-defi- brillators for treatment of sustained ventricular arrhythmias in patients with Chagas' heart disease:comparison with a control group treated with amiodarone alone[J]. Europace, 2014,16 ( 5 ) : 674-680.
  • 8苏丹霞,胡梅荣.胺碘酮治疗快速性心律失常的临床观察[J].中国现代医生,2008,46(2):84-85. 被引量:27
  • 9游建明,陈乐鸿,陈泽芳,杜育彬.胺碘酮治疗老年室性心律失常患者的临床疗效观察[J].大家健康(学术版),2012(17):34-35. 被引量:5
  • 10张晶敏,陈翠薇,周岩,董建伦.胺碘酮治疗室上性心动过速50例临床观察[J].当代医学,2010,16(6):146-146. 被引量:3

引证文献4

二级引证文献28

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部