他汀类药物的多效性及对糖代谢的影响

The pleiotropic effects and impact on glucose metabolism of statins

他汀类药物应用于高脂血症患者及心脑血管疾病的一二级预防,越来越多的研究表明,他汀类在降脂、抗炎、保护血管内皮、稳定动脉粥样硬化斑块、抗心律失常同时,还会影响患者的血糖水平。因此,全面了解他汀类药物的作用,指导临床用药意义重大。

Statins are applied in the patients with hyperlipidemia and in the cardiovascular and cerebrovascular diseases primary and secondary prevention.More and more studies indicate that statins not only reduce blood lipid,have antiinflammatory action,protect the vascular endothelium,but also affect glucose level.Therefore,comprehensive understanding of the role of statins help guide the clinical treatment.