综合运用干预措施对我院抗菌药物应用的效果评价

Comprehensive use of interventions on the evaluation of antimicrobial applications in a hospital of Anhui province

目的评价综合干预措施对干预前后抗菌药物应用的对比变化以及综合干预的效果,规范医师合理使用抗菌药物,提高治疗水平。方法通过制定规范、加强教育、分级管理、检查反馈等措施来干预临床抗菌药物不合理使用现象。对医院干预前(2012年1—4月份)和干预后(2012年5—8月份)住院患者抗菌药物使用情况进行统计、对比和分析。结果干预后住院患者抗菌药物使用比例由66.90%下降至60.88%,住院患者抗菌药物使用强度由75.91DDD下降至62.93DDD,Ⅰ类手术切口抗菌药物预防使用率由100%下降至29.58%,微生物送检率由17.71%提高至30.62%,干预效果显著。结论综合干预措施对促进医院抗菌药物合理使用是可行的和有效的。

Objective To evaluate （：omprenensive interventions changes on the antimicrobial agents before and alter the intervention, as well as the effect of the intervention, so as to improve the physic：Jan rational use of antimicrobial drags and the treatment level. Methods Irrational use of antimicrobial drugs was intervened by norms, measures to strengthen education, management at different levels,inspec- tion and feedback. Statistics were compared and analyzed the use of antibacterial drugs （5--8 months）among hospitalized patients before the intervention（ 1--4 months） and after the intervention were compared and analyzed. Results Inpatient antimierobial use proportion af- ter the intervention decreased fi＇om 66.90% to 60.88%. Inpatient antimicrobia] use strength from 75.91DDD to 62.93DDD. The atiliza- tion rate of I class surgical incision antimicrobial prophylaxis fell to 29.58% from 100% , microbial censorship rate increazed from 17. 71% to 30.62%. The intervention effect is remarkable. Conclusion Comprehensive intelwentions to promote rational use of hospital an- timicrobial agents is feasible and effective.