2003～2010年我院早产儿视网膜病变筛查治疗结果临床分析

Clinical analysis of screening treatment outcomes of retinopathy of prematurity in our hospital from 2003 to 2010

目的观察早产儿视网膜病变（ROP）筛查以及治疗情况。方法跟踪随访烟台市莱阳中心医院眼科2003年7月~2010年7月收治的1379例2758只眼ROP患儿,对于1、2期病变,进行2周1次的复查,而对于3期患儿,进行激光光凝治疗,对于出现视网膜脱离的4、5期患儿给予巩膜环扎手术、闭合式玻璃体切割手术治疗,观察治疗后患儿恢复情况。结果 400只眼达到治疗要求,经过治疗后345只眼ROP退化,55只眼出现视网膜结构不良;而2358只无需进行治疗的ROP患眼病变均退化,共2703只眼出现自行或治疗后退化,45只眼进展至4、5期,经手术治疗后,疗效不佳。结论早期筛查以及治疗能够降低视网膜结构不良的发生率。

Objective To observe the screening and treatment condition of retinopathy of prematurity （ROP）. Methods From July 2003 to July 2010, 1379 cases 2758 eyes of patients with ROP treated in Ophthalmology Department, Laiyang Central Hospital of Yantai City were selected. Reexamine was given for patients with phase 1 or 2 lesions by once two weeks, laser photocoagulation treatment was given for patients with phase 3 lesions, while, patients with phase 4 or 5 lesions of amotio retinae received treatment of scleral cerclage surgery and closed vitrectomy. The recovery of children was observed after treatment. Results 400 eyes had reached treatment requirements, and after treatment, 345 eyes of them had ROP degradation, the other 55 eyes had retinal dysplasia. 2358 ROP eyes without treatment had degradation. The total of 2703 eyes had degradation spontaneously or after treatment. Poor surgery efficacy was observed in 45 eyes which had progressed to phase 4 or 5 lesions. Conclusion Early screening and treatment can reduce the incidence of retinal dysplasia.