老年陈旧性心肌梗死患者介入治疗的效果观察

Effect observation on interventional therapy in elderly patients with old myocardial infarction

目的观察老年陈旧性心肌梗死介入治疗和药物治疗的临床效果。方法选择沈阳军区总医院2009年1～12月治疗的老年陈旧性心肌梗死患者112,随机分为药物组及介入组,每组各56例。介入组给予介入法治疗,药物组患者给予常规药物治疗,观察两组患者治疗后心脏事件发生情况、再住院情况和生存情况以及心功能改善情况。结果①介入组患者心脏事件发生率为26.8%(15/56),药物组患者心脏事件发生率为76.8%(43/56),介入组心脏事件发生率明显高于药物组,差异有统计学意义(P<0.05)。②介入组患者再住院率为30.4%(17/56),生存率为96.4%(54/56);药物组患者再住院率为83.9%(47/56),生存率为89.3%(50/56),介入组患者再住院率低于药物组,且介入组生存率高于药物组,两组比较差异有统计学意义(P<0.05)。③介入组治疗后心功能≥3级比例低于药物组,心功能<3级比例高于药物组,差异有统计学意义(P<0.05)。结论老年陈旧性心肌梗死患者介入治疗效果明显,可有效提高患者生存率、降低心脏事件发生率和再住院率,改善心功能,值得临床应用。

Objective To observe the clinical effect of elderly patients with old myocardial infarction interventional therapy and drug treatment. Methods 112 aged patients with old myocardial infarction from January to December 2009 in General Hospital of Shenyang Military Area Command were selected and randomly divided into drug group and intervention group with 56 cases in each group. Patients in intervention group were treated with interventional therapy, patients in drug group were given routine drug treatment; cardiac events incidence, hospitalization, survival and the improvement of heart function situation after the treatment in the two groups were observed. Results （2）The cardiac events incidence in intervention group was 26.8% （15/56）, the cardiac events incidence in drug group was 76.8% （43/56）, the difference was statistically significant （P 〈 0.05）. （2）The hospital readmission rate in intervention group was 30.4% （17/56）, the survival rate was 96.4% （54/56）; the hospital readmission rate in drug group was 83.9% （47/56）, the survival rate was 89.3% （50/56）, the hospital readmission rate in intervention group was lower than that in drug group, the survival rate in intervention group was higher than that in drug group, the differences were statistically significant （P 〈 0.05）. （3）The proportion of cardiac function ≥3 grade in intervention group was lower than that in drug group, the proportion of cardiac function 〈3 grade in intervention group was higher than that in drug group, the differences were statistically significant （P 〈 0.05）. Conclusion The clinical effect of elderly patients with old myocardial infarction interventional therapy is obvious, it can effectively improve the survival rate of patients, and reduce the incidence of cardiac events and rehospitalization rate, improve the heart function, is worthy of clinical ap- plication.