纤维支气管镜肺泡灌洗治疗医院获得性重症肺炎的疗效分析

Curative effect analysis of bronchoalveolar lavage in treatment of nosocomial severe pneumonia

目的观察临床应用纤维支气管镜肺泡灌洗治疗医院获得性重症肺炎的效果。方法选取本院2009年6月～2012年3月收治的60例医院获得性重症肺炎患者,按随机数字表法分为观察组和对照组各30例,对照组给予常规抗生素综合治疗,观察组在此基础上给予纤维支气管镜肺泡灌洗治疗,观察两组患者治疗后的临床疗效、细菌培养阳性率及肺部感染评分情况。结果治疗后观察组总有效率高于对照组(P<0.01);细菌培养阳性率及肺部感染评分两组均较治疗前降低,观察组降低幅度明显高于对照组,差异有统计学意义(P<0.01)。结论纤维支气管镜肺泡灌洗是治疗医院获得性重症肺炎安全、有效的方法,值得推广与应用。

Objective To observe the effect of bronchoalveolar lavage in treatment of nosocomial severe pneumonia in clinic. Methods 60 cases of patients with nosoeomial severe pneumonia,who treated in our hospital from June 2009 to March 2012,they were selected and randomly divided into observation group and control group with 30 cases in each group.Patients in control group were given comprehensive treatment of conventional antibiotic,and patients in observa- tion group added bronchoalveolar lavage.The clinical effect,positive rate of bacteria culture and pulmonary infection score after treatment in two groups were observed. Results After treatment,the total effective rate of observation group was higher than that of control group （P〈0.01）,the positive rate of bacteria culture and pulmonary infection score in two groups were decreased significantly,and the reduction in observation group was significantly higher than that in control group （P〈0.01）,it had statistical significance. Conclusion Bronchoalveolar lavage is a safe and effective method in treatment of nosocomiat severe pneumonia,it worthy of promotion and application.