急性脑梗死和心肌梗死危险因素的对比分析

Analysis on the risk factors of acute myocardial infarction and acute cerebral infarction

目的 探讨急性脑梗死与急性心肌梗死危险因素的异同.方法 分析115例急性脑梗死患者和108例急性心肌梗死患者的性别、年龄、高血压病史、糖尿病史、生活方式因素等以及入院后血糖、血脂、尿酸、纤维蛋白原等生化资料.结果 急性脑梗死患者高血压病发病率、血清胆固醇（TC）、低密度脂蛋白胆固醇（LDL-C）水平高于急性心肌梗死患者（P＜0.05）；急性心肌梗死患者尿酸（UA）、纤维蛋白原（FIB）水平高于脑梗死患者（P＜0.01或P＜0.05）.结论 高血压与TC、LDL-C水平作为发病危险因素与脑梗死的密切程度高于心肌梗死；纤维蛋白原和尿酸异常在急性心肌梗死的发病中可能有更明显的作用.

Objective To explore the difference of the risk factors between acute myocardial infarction（AMI） and acute cerebral infarction（ACI）.Methods Case history,life style and biochemical indicators in admission including blood glucose,blood lipid,uric acid （UA） and plasma flbrinogen （FIB） in 108 AMI and 115 ACI patients were collected.Results Prevalence of hypertension in ACI patients （80%） was higher than that in AMI patients（66.7%,P 〈0.05）.Mean levels of total cholesterol（TC）,low density lipoprotein（LDL-C） in ACI patients were higher than those in AMI （P 〈 0.05）.The mean level of plasma fibrinogen in AMI patients was higher than that in ACI patients （P 〈 0.05）.The mean levelof UA in AMI patients was significantly higher than that in ACI patients （P 〈 0.01）.Conclusion The mean level of plasma fibrinogen,UA have more close relationship with myocardial infarction than acute cerebral infarction.Prevalence of hypertension has more close relationship with acute cerebral infarction.In the acute stage,the mean levels of TC and LDL-C in cerebral infarction patients are higher than those in AMI patients.