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可溶性尿激酶型纤溶酶原激活物受体的研究进展 被引量：10

Research progress of soluble urokinase-type plasminogen activator receptor
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摘要 可溶性尿激酶型纤溶酶原激活物受体(suPAR)是近年来发现的新型炎症标志物,其反映机体的免疫活化水平,在多种疾病中升高。该文就suPAR的结构及其在疾病诊断、病情监测、预后评估中的研究进展作一综述。 Soluble urokinase-type plasminogen activator receptor （suPAR） is a new type of inflam-matory markers discovered in recent years, which reflects the level of immune activation, elevated in a variety of diseases. In this paper, suPAR structure and its research progress in disease diagnosis, disease monitoring, prognosis were reviewed.
作者 常敏婵 曾勉
机构地区 中山大学附属第一医院MICU
出处 《新医学》 2013年第7期442-445,共4页 Journal of New Medicine
关键词 可溶性尿激酶型纤溶酶原激活物受体 炎症 标志物 预后 Soluble urokinase-type plasminogen activator receptor Inflammatory Marker Prognosis
分类号 R737.31 [医药卫生—肿瘤]
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参考文献15

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同被引文献72

  • 1张天嵩,韩镭,吴银根,王宏长,于素霞.肺纤煎对博莱霉素A_5致肺纤维化小鼠肺组织TNF-αTNF-αmRNA表达的影响[J].中医药学刊,2004,22(8):1474-1476. 被引量：6
  • 2魏绍斌,王妍.防治慢性盆腔炎反复发作的相关对策探讨[J].辽宁中医杂志,2006,33(9):1101-1102. 被引量：22
  • 3A. Heraclides,T. M. Jensen,S. S. Rasmussen,J. Eugen-Olsen,S. B. Haugaard,K. Borch-Johnsen,A. Sandb?k,T. Lauritzen,D. R. Witte.The pro-inflammatory biomarker soluble urokinase plasminogen activator receptor (suPAR) is associated with incident type 2 diabetes among overweight but not obese individuals with impaired glucose regulation: effect modification by smoking and body weight status[J].Diabetologia.2013(7)
  • 4Gergely Toldi,Gabriella Bek?,Gabriella Kádár,Emília Mácsai,László Kovács,Barna Vásárhelyi,Attila Balog.Soluble urokinase plasminogen activator receptor (suPAR) in the assessment of inflammatory activity of rheumatoid arthritis patients in remission[J].Clinical Chemistry and Laboratory Medicine.2013(2)
  • 5Wei Chen,Wei-Quan Jin,Lian-Feng Chen,Taiya Williams,Wen-ling Zhu,Quan Fang.Urokinase receptor surface expression regulates monocyte migration and is associated with accelerated atherosclerosis[J].International Journal of Cardiology.2011(2)
  • 6Yara Backes,Koenraad Sluijs,David Mackie,Frank Tacke,Alexander Koch,Jyrki Tenhunen,Marcus Schultz.Usefulness of suPAR as a biological marker in patients with systemic inflammation or infection: a systematic review[J].Intensive Care Medicine.2012(9)
  • 7.Blood chemistry markers for evaluation of inflammatory activity in Crohn’s disease during infliximab therapy[J].Scandinavian Journal of Gastroenterology.2011(4)
  • 8Boris K. Pliyev,Tatiana I. Arefieva,Mikhail Yu. Menshikov.Urokinase receptor (uPAR) regulates complement receptor 3 (CR3)-mediated neutrophil phagocytosis[J].Biochemical and Biophysical Research Communications.2010(2)
  • 9Nobuo Nagai,Kiyotaka Okada,Naoyuki Kawao,Chikako Ishida,Shigeru Ueshima,Desire Collen,Osamu Matsuo.Urokinase-type plasminogen activator receptor (uPAR) augments brain damage in a murine model of ischemic stroke[J].Neuroscience Letters.2007(1)
  • 10Dr Agati VD, Kaskel FJ,Falk RJ. Focal segmental glomer- ulosclerosis[J]. N Engl J Med,2011,365(25) ..2398-2411.

引证文献10

二级引证文献52

新医学
2013年 第7期

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