鞘内连续输注小剂量舒芬太尼用于分娩镇痛的临床观察

The clinical research of continuous intrathecal infusion of small doses sufentanil for labor analgesia

目的:研究鞘内连续输注小剂量舒芬太尼用于分娩镇痛的临床效果及对分娩的影响。方法:40例单胎初产妇随机均分成两组,Ⅰ组为未镇痛组,Ⅱ组为鞘内舒芬太尼镇痛组。在2组孕妇"宫口开3 cm、1 h后、2 h后、4 h后、宫口开全时"监测VAS镇痛评分、子宫收缩力的变化,并记录第一、二产程时间、催产素的使用率、分娩方式以及胎儿Apgar评分等。结果:和Ⅰ组比较,分娩镇痛后Ⅱ组VAS镇痛评分明显降低(P<0.01),但2组孕妇的子宫收缩力,第一、二产程时间,催产素的使用率,分娩方式,以及胎儿Apgar评分等各项指标无显著性差异(P>0.05)。结论:鞘内连续输注小剂量舒芬太尼用于分娩镇痛镇痛效果良好,不影响孕妇的子宫收缩,第一、二产程,分娩方式,以及胎儿Apgar评分,是一种安全、满意的镇痛方法。

OBJECT1VE To investigate the effect of intrathecal continuous intuson ot smalt algesia. METHODS Forty ASA physical status Ⅰ or Ⅱ full-term primiparous parturients were randomly divided into two groups （ Ⅰ group no epidural labor analgesia and Ⅱ group intrathecal sufentanil analgesia group）, and each group was twenty women. VAS pain scores, uterine contractility, the first and second stage of labor time, utilization of oxytocin, mode of deliv- ery and fetal Apgar score were observed when uterine cervical dilatation to 3cm, one hour later, two hour later, four hour later and the whole cervix. RESULTS Compared with group, Ⅱ group VAS pain scores decreased significantly after labor anal- gesia in group （P〈0. 01）, but uterine contractility, the first and second stage of labor time, utilization of oxytocin, mode of delivery and fetal Apgar was same in two group（P〈0. 05）. CONCLUSION Intrathecal continuous infusion of small doses of sufentanil for labor analgesia have excellent analgesic effect, have no effect on uterine contractility, the first and second stage of lahor time, utilization of oxytocin, mode of delivery and fetal Apgar, and is a security, satisfactory analgesia method.