热敏灸配合药物治疗高泌乳素血症所致不孕疗效观察

Therapeutic Observation on Heat-sensitive Moxibustion plus Medicine for Infertility Induced by Hyperprolactinemia

目的观察热敏灸为主治疗高泌乳素血症所致不孕的临床疗效。方法将85例高泌乳素血症不孕患者随机分为治疗组44例和对照组41例。治疗组采用热敏灸配合口服溴隐亭治疗,对照组采用单纯口服溴隐亭治疗。观察两组治疗前后外周血泌乳素(PRL)水平,比较两组临床疗效及妊娠率和流产率。结果治疗组总有效率为95.5%,对照组为90.2%,两组比较差异无统计学意义(P>0.05)。两组治疗后血清PRL水平与同组治疗前比较,差异均具有统计学意义(P<0.05)。治疗组治疗前后血清PRL水平差值与对照组比较,差异无统计学意义(P>0.05)。治疗组患者治疗后妊娠率及流产率分别为59.1%和3.8%,对照组分别为36.6%和26.7%,两组比较差异均具有统计学意义(P<0.05)。结论热敏灸配合药物是一种治疗高泌乳素血症所致不孕的有效方法。

Objective To observe the clinical efficacy of treating infertility induced by hyperprolactinemia majorly with heat-sensitive moxibustion. Method Eighty-five patients with infertility induced by hyperprolactinemia were randomized into a treatment group of 44 cases and a control group of 41 cases. The treatment group was intervened by heat-sensitive moxibustion plus oral Bromocriptine, and the control group was by Bromocriptine alone. Peripheral prolactin （PRL） levels of the two groups were observed before and after treatment; therapeutic efficacy, pregnancy rate, and abortion rate were compared between the two groups. Result The total effective rate was 95.5% in the treatment group versus 90.2% in the control group, and the difference was insignificantly significant （P〉0.05）. The two groups both had marked changes in serum PRL level after treatment （P〈0.05）. The change of serum PRL level in the treatment group was insignificantly different from that in the control group （P〉0.05）. The pregnancy rate and abortion rate were respectively 59.1% and 3.8% in the treatment group versus 36.6% and 26.7% in the control group, and the differences were statistically significant （P〈0.05）. Conclusion Heat-sensitive moxibustion plus medication is an effective method in treating infertility induced by hyperprolactinemia.