摘要
目的观察灸法退热的体温中枢效应与穴区施灸面积之间的关系。方法选用新西兰兔30只,分为A组(静脉注射内毒素造模)、B组(注射内毒素后行40℃灸,施灸圆面直径为10 mm)、C组(注射内毒素后行40℃灸,施灸圆面直径为20 mm)、D组(注射内毒素后行48℃灸,施灸圆面直径为10 mm)、E组(注射内毒素后行48℃灸,施灸圆面直径为20 mm),每组6只。实验在动物肌肉松弛、行人工呼吸条件下进行。穴位取至阳穴,以视前区下丘脑前部热敏神经元放电为指标,观察5组处理对热敏神经元放电的影响。结果 B组与C组、D组与E组比较,中枢温度敏感神经元的放电变化有明显差异,这种差异是由于施灸面积的改变而引起,经统计学检验,具有显著的正相关关系。结论穴位施灸面积的大小能够影响疗效。
Objective To investigate a relationship between the reaction of thermoregulator centers to antipyretic moxibustion and its active area at the point. Methods Thirty New Zealand rabbits were enrolled and allocated to groups A (intravenous injection of endotoxin for model making), B (intravenous injection of endotoxin followed by 40℃ moxibustion with an active area of 10 mm in diameter), C (intravenous injection of endotoxin followed by 40℃ moxibustion with an active area of 20 mm in diameter), D (intravenous injection of endotoxin followed by 48℃ moxibustion with an active area of 10 mm in diameter) and E (intravenous injection of endotoxin followed by 48℃moxibustion with an active area of 20 mm in diameter). The experiment was performed under the relaxation of animal muscles and artificial respiration. Point Zhiyang was selected. Discharge of temperature-sensitive neurons in the preoptic-anterior hypothalamus was used as an index. The effect of treatment on discharge of temperature-sensitive neurons was observed in the five groups. Results Comparisons between groups B and C and between groups D and E showed significant differences in discharge of central temperature-sensitive neurons. The differences were caused by the change in the active area of moxibustion. Statistical analysis showed a significant positive correlation. Conclusion The size of the active area of moxibustion at the point can influence the therapeutic effect.
出处
《上海针灸杂志》
2013年第7期600-603,共4页
Shanghai Journal of Acupuncture and Moxibustion
基金
四川省应用基础研究计划资助项目(05JY029-043)