盐酸特比萘芬片治疗真菌性皮肤病的临床分析及安全性观察

Clinical analysis and safety observation of Terbinafin Hydrochloride Tablets in the treatment of mycosis

目的评价盐酸特比萘芬片治疗真菌性皮肤病的临床疗效和不良反应。方法 360例真菌性皮肤病患者,随机分成3组,分别给予盐酸特比萘芬片口服加外用,伊曲康唑口服,氟康唑口服治疗。结果 3组患者经治疗后,特比萘芬组总有效率明显优于其他2组。结论特比萘芬是治疗皮肤真菌病的有效药物,其远期疗效优于伊曲康唑和氟康唑,值得临床推广应用。

Objective To evaluate the clinical efficacy and adverse reaction in the treatment of mycosis with Terbinafin Hyrochloride Tablets. Methods Three hundred and sixty patients were randomly assigned into 3 groups, oral and external use of Terbinafin H ydrochloride Tablets group,oral administration of itraconazle group,and Fluconazole group. Results After the trial on three dif- ferent groups of patients, the efficiency of Terbinafin Hydrochloride Tablets is evidently better than the others. Conclusion Terbinafin Hydrochloride Tablets were long-term effective and safe in treating mycosis when compared with Itraconazle and Fluconazole. Terbinafin Hydrochloride Tablets is worth of clinical application.