我院2004～2012年药品不良反应报告分析

Analysis of adverse drug reaction reports from 2004 to 2012 in our hospital

目的对我院药品不良反应(adverse drug reaction,ADR)报告和监测情况进行分析,总结有效的工作模式,进一步提高药品不良反应监测质量。方法对我院2004年1月～2012年12月收到的ADR报告,按ADR报告数量、报告科室、引起药品不良反应的药品种类等进行分析。结果 ADR报告919份,上报科室共25个,涉及药品127种,其中抗菌药物73种(57.48%),居首位;其次是中药注射剂24种(18.90%)。结论临床必须重视药品不良反应;对抗菌药物和中药注射剂应重点进行监测;有效的工作模式对ADR监测工作有推动作用。

Objective To improve the effective working modes on ADR reports and monitoring by analyzing the adverse drug reaction （ADR） reports and monitoring in our hospital. Methods ADR reports collected in our hospital from January 2004 to December 2012 were analyzed in aspects of ADR report quantities, the departments, drug categories inducing ADR etc. Results There were 919 cases of ADR reports collected,and departments were 25 ~there were 127 species of drug involved,among which 73 species of antibiotics were included （57.48 % ）, ranking in the top. Next was 24 species of traditional Chinese medicine injections （18.90 %）. Conclusion Great attention should be attached to the ADR monitoring in clinic, especially the antibiotics and traditional Chinese medicine injections.