Cu_(0.05)Zn_(0.95)O/聚吡咯纳米复合物的制备和抗菌性能

Preparation and antibacterial activities of Cu_(0.05)Zn_(0.95)O/polypyrole nanocomposites

在CTAB/正己烷/正丁醇/水(W/O)四元反相微乳液体系中原位聚合制备了铜掺杂氧化锌/聚吡咯(CZ/PPy)纳米复合物.用X射线衍射仪、扫描电子显微镜、透射电子显微镜、红外光谱仪和紫外-可见光谱仪分别表征了样品的结构、形貌和光谱学性能;以大肠杆菌(Escherichia coli)、金黄色葡萄球菌(Staphylococcus aureus)和白色念珠菌(Candida albicans)为测试菌株研究了样品的抗菌活性.结果表明PPy包覆在CZ粒子表面形成了核-壳结构的CZ/PPy复合物,PPy链与CZ纳米粒子之间存在一定的相互作用;复合物的抗菌性能优于CZ,且抗菌活性随着CZ含量的增加而增大.

Cu0.05Zn0.95O/polypyrole （CZ/PPy） nanocomposites were prepared by in situ polymerization method in a quaternary inverse microemulsion （W/O） consisting of CATB/n-hexane/n-butanol/H2O.The structure,morphology and spectroscopy performances of the samples were characterized by powder X-ray diffractometer （XRD）,scanning electron microscope （SEM）,transmission electron microscope （TEM）,Fourier transform infrared （FTIR） spectroscope and ultraviolet-visible （UV-vis） spectroscope.The antimicrobial activities of the samples against Staphylococcus aureus,Escherichia coli and Candida albicans were carried out using powder inhibition zone,minimum inhibitory concentration and minimal bactericidal concentrations methods.The results showed that the CZO nanoparticles were embedded uniformly in the PPy matrix to form the CZ/PPy composites with the core-shell structure,and some interactions between PPy and CZO particles must be existing in the composites.The CZ/PPy nanocomposites exhibited excellent antibacterial and bactericidal activities against the growth of microorganisms,and were prior to that of CZ.Their activities increased with the increasing of the CZ content in the CZ/PPy composites.