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胃液抗-H.pylori IgA对幽门螺杆菌根除效果的影响 被引量:1

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摘要 目的改变胃液pH值,通过测定胃液抗-H.pylori IgA的含量,阐明在不同胃液pH值下根除H.pylori的意义。方法消化性溃疡患者120例随机分成治疗组及对照组,治疗组第1周给予奥美拉唑肠溶胶囊20mg口服,2次/d,第2周加用抗H.pylori药物,抗H.pylori治疗结束后继续完成治疗疗程。对照组第1周直接给予抗H.pylori治疗,抗H.pylori治疗结束后继续完成治疗疗程。2组均在抗H.pylori治疗前后通过胃镜吸取胃液测定pH值,并采用ELISA方法测定胃液抗-H.pylori IgA含量。结果胃液pH值与抗-H.pylori IgA含量呈正相关。结论应用抑酸剂改变胃液pH值,使胃液中抗-H.pylori IgA含量发生相应变化,对H.pylori的根除率具有一定的影响。
出处 《河北医科大学学报》 CAS 2013年第7期805-807,共3页 Journal of Hebei Medical University
基金 河北省卫生厅医学科学研究课题(20100249)
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