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干燥综合征的非生物制剂治疗现状 被引量:2

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摘要 干燥综合征的治疗主要分为针对外分泌腺受累(干燥症状的改善和缓解)和针对内脏损害两大类。前者以刺激外分泌腺体的分泌和局部润滑保护为目的,以拟副交感神经作用药为代表,如毛果芸香碱和西维美林(M1受体激动剂);系统性病变的治疗以TNFa抑制剂以及免疫抑制剂为主,目的在于针对该病的预后不良因素和内脏(如肺间质纤维化、自身免疫性肝病)或严重的血管炎和神经系统受累的治疗。
出处 《中国医刊》 CAS 2013年第7期16-17,共2页 Chinese Journal of Medicine
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