摘要
以Mg-3.13Nd-0.16Zn-0.41Zr(质量分数,%,JDBM)镁合金为研究对象,研究挤压态JDBM的细胞毒性和腐蚀性能。通过热挤压工艺制备出心血管支架用镁合金微管,并观察其组织。采用激光切割、电化学抛光等工艺制备出心血管支架,测试支架表面粗糙度和径向支撑力。结果表明,JDBM镁合金对内皮细胞无毒性,具有理想的耐蚀性能和腐蚀方式;制备出的心血管支架的径向支撑力超过正常成年人血管收缩压的4倍,满足心血管支架对力学性能的要求。
Mg-3.13Nd-0.16Zn-0.41Zr （wt%, JDBM） alloy was chosen and the cell toxicity and corrosion property of the as-extruded JDBM were studied. Magnesium tube was prepared by hot extrusion processing and the microstructure of the tube was observed. The cardiovascular stent was prepared by laser cutting and electrochemical polishing processes. The surface roughness and radial expansion force were tested. The results show that JDBM magnesium alloy exhibits no cell toxicity of Endothelial cell, good corrosion resistance and corrosion mode. The radial expansion force of the prepared cardiovascular stents is over 4 times than that of the maximal vascular compression pressure of normal adult, which meets the requirement of the mechanical properties for cardiovascular stents.
出处
《稀有金属材料与工程》
SCIE
EI
CAS
CSCD
北大核心
2013年第6期1300-1305,共6页
Rare Metal Materials and Engineering
基金
中国博士后科学基金(20100470030)
南京工程学院引进人才科研启动基金项目(YKJ201201)
关键词
生物可降解镁合金
心血管支架
细胞毒性
腐蚀性能
径向支撑力
biodegradable magnesium alloy
cardiovascular stent
cell toxicity
corrosion property
radial expansion force
