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地佐辛复合舒芬太尼对上腹部手术后镇痛效应与免疫功能的影响 被引量:5

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摘要 将上腹部手术治疗的83例患者随机分为两组,观察组使用地佐辛复合舒芬太尼术后镇痛,对照组单独使用舒芬太尼。比较两组患者不同时间点视觉模拟评分(VAS评分)及不良反应发生情况,ELISA法测定其血浆IL-6、IL-10含量。结果两组患者手术后各时间点VAS评分无显著差异(P>0.05);比较发现观察组不良反应发生率明显低于对照组,分别为9.3%和22.5%,差异显著(P<0.05);比较两组患者血浆IL-6、IL-10发现,术后IL-6水平在对照组均高于观察组,而IL-10的水平对照组均低于观察组。地佐辛复合舒芬太尼对上腹部手术患者术后镇痛效果明显,不良反应的发生率较低,同时对免疫功能的影响较小,值得在临床上推广使用。
作者 魏双双 刘庆
出处 《现代诊断与治疗》 CAS 2013年第6期1341-1342,共2页 Modern Diagnosis and Treatment
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