前列腺等离子切除术治疗晚期前列腺癌并膀胱出口梗阻的临床观察

The clinical observation of prostate plasma resection in the treatment of advanced pros- tate cancer with bladder outlet obstruction

目的 探讨经尿道等离子电切（PKRP）治疗晚期前列腺癌（PCa）伴膀胱出口梗阻（BOO）的临床疗效.方法 回顾分析2008年8月至2011年8月24例采用PKRP治疗的PCa患者,收集患者临床资料,随访6个月.对手术前后患者国际前列腺症状评分（IPSS）、生活质量评分（QOL）、最大尿流率（Qmax）、残余尿量（RV）进行比较.结果 24例患者术后下尿路症状均明显减轻,IPSS由术前（18.96±4.28）分降至（8.51±2.52）分（P＜0.05）、QOL由术前（4.51±0.52）分降至（1.51±0.01）分（P＜0.05）,Qmax由术前（9.2±0.6） ml/s增至（19.3±2.3）mL/s（P＜0.05）、RV由术前（201.4±12.4）mL降至（42.6±4.6） mL（P＜0.05）,随访期间无死亡病例.结论 晚期伴BOO的PCa患者,经PKRP治疗是一种安全、有效的治疗方法,能够有效改善患者生活质量.

Objectives To investigate clinical efficacy of the plasma electtonics resection （PKRP） for the treatment of advanced prostate cancer with bladder outlet obstruction.Methods Retrospective analysis of 2008 August to 2011 August 24 cases treated by PKRP in patients with PCa,collected from patients with clinical data,followed up for 6 months,before and after operation on the patients with the International Prostate Symptom Score （IPSS）,quality of life score（QOL）,maximal urinary flow rate （Qmax）,residual urine volume（RV） were compared.Results 24 cases of patients with lower urinary tract symptoms were significantly reduced,IPSS preoperatively by （18.96 ± 4.28） to （8.51 ±2.52） divided into（P 〈0.05）,QOL preoperatively by （4.51 ± 0.52） to （1.51 ±0.01） divided into（P 〈0.05）,Qmax by operation before（9.2 ±0.6） ml/s to （19.3 ±2.3） ml/s （P 〈0.05）,RV preoperatively by （201.4 ± 12.4） ml to （42.6 ± 4.6） ml （P 〈 0.05）,during the follow-up period no deaths.Conclusions Conclusion：the late with BOO PCa patients,plasma electtonics resection therapy is a safe,effective treatment,can improve the life quality of the patients.