腹腔镜小儿腹股沟斜疝高位结扎术对患儿外周血C-反应蛋白的影响

Effect of laparoscopic indirect inguinal hernia on the serum level of CRP in children

目的探讨腹腔镜小儿腹股沟斜疝高位结扎手术前后患儿外周血C反应蛋白(C-reaction protein,CRP)的变化。方法将56例腹股沟斜疝的患儿随机分为腹腔镜组(L组)与传统手术组(T组),比较两组患儿术前1 d、术后8 h、24 h、48 h外周血CRP值。结果两组患者术后8 hCRP均明显高于术前,并且传统手术组高于腹腔镜组;术后24 h,腹腔镜组已经下降,而传统手术组仍然高于术前;术后48 h,两组血清CRP回落接近术前水平。结论腹腔镜小儿腹股沟斜疝高位结扎术引起CRP的变化较小,故对患儿机体的创伤较小,值得临床推广。

Objective To investigate the changes of CRP level after laparoscopic indirect inguinal hernia in children. Methods Fifty-six patients were divided into two groups randomly,the laparoscopie group （L group） and traditional group（ T group）. The levels of C-reacrion protein（CRP） were evaluated one day before operation as well as 8 hours, 24 hours, and 48hours postoperatively. Result Eight hours after operation, serum level of CRP increased in both groups, but the increment was more obvious in T group than in L group. Twenty-four hours after operation, serum level of CRP recovered to the preoperative level in L group but not in T group. Forty-eight hours after operation, serum level of CRP recovered to the preoperative level in T group. Conclusions Since the change of CRP level is smaller after laparoscopic surgery than that after open surgery,we consider that laparoscopic hemiotomy exerts less trauma effects in children than traditional open surgery, indicating its broad clinical application.