摘要
线粒体是真核细胞中最重要的细胞器,其结构有4个区隔,外膜、内膜、膜间隙和基质.线粒体转运系统包括线粒体外膜易位子、内膜易位子、胞质中的可溶性因子、膜间隙和线粒体基质.文章重点介绍了线粒体前体蛋白向内膜、膜间隙和基质转运的运输机制及其转运体TOM40复合体、TIM23复合体、小Tim蛋白复合体和二硫键传递系统的结构和功能.
Mitochondria are the most important organelles in eukaryotic cells. The spatial structure of mitochondria including four regions： outer membrane, inner membrane, intermembrane space and matrix. Mitochondrial trans- port system comprises the translocase of the outer and inner mitochondrial membrane, soluble factors of the cyto- plasm, intermembrane space and matrix. The transportation mechanism of mitochondrial precursor protein into in- ner membrane, intermembrane space and matrix are emphasized in this paper. The structure and function of trans- locators including TOM40 complex, TIM23 complex, small Tim proteins and the disulfide relay system are also dis- cussed in the present paper.
出处
《南京晓庄学院学报》
2013年第3期76-78,共3页
Journal of Nanjing Xiaozhuang University
基金
江苏省自然科学基金青年项目(BK2012073)资助
关键词
线粒体
运输蛋白
分子伴侣
mitochondria
transportprotein
chaperones
