期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

B7-H1与恶性肿瘤的相关研究进展 被引量：1

下载PDF
导出
摘要 恶性肿瘤简单来讲,是指机体组织细胞在后天环境或先天遗传等多种致癌因素作用下发生的恶性病变。预后不良,死亡率较高。严重威胁着人类健康。近年来,一些恶性肿瘤相关蛋白质分子生物学标记物被用于病情发生发展、预后及治疗效果的判断，本研究就B7-H1在恶性肿瘤组织中表达的意义做一综述。
作者 高辉 李晓凤
机构地区 内蒙古自治区包头肿瘤医院综合内科
出处 《中国临床保健杂志》 CAS 2013年第2期211-213,共3页 Chinese Journal of Clinical Healthcare
基金 包头市卫生科研基金资助项目(2010s2001-5)
关键词 恶性肿瘤组织 B7-H1 分子生物学标记物 预后不良 相关蛋白质 恶性病变 致癌因素 先天遗传
分类号 R730.5 [医药卫生—肿瘤]
  • 相关文献

参考文献13

  • 1Blank C, Mackensen A. Contribution of the PD-L1/PD-I pathway to T-cell exhaustion:an update on implications for chronic infections and tumor evasion [ J ]. Cancer Im- munol Immun ,2007,56 ( 5 ) :739-745.
  • 2Brown JA, Dorfman DM, Ma FR, et al. Blockade of pro- grammed death-1 ligands on dendritic cells activation and cytoking production [ J ]. J Irmnunol, 2006, 170 ( 3 ) : 1257- 1266.
  • 3刘书漫,孟青,张钦宪,王盛典,刘占举,张谢夫.B7-H1及其受体PD-1在胃癌组织中的表达与意义[J].中华肿瘤杂志,2008,30(3):192-195. 被引量：23
  • 4Chen X,Liu S,Wang L,et al. Clinical significance of 137- H1 (PD-L1) expression in human acute leukemia[ J]. Cancer Biol Ther ,2008 ,7 (5) :622-627.
  • 5Parsa AT, Waldron JS, Panner A, et al. Loss of tumor sup- pressor PTEN function in creases B7-H1 expression and im- munoresistance in glioma[ j]. Nat Med,2007,13( 1 ) :84-88.
  • 6Tsushma F, Yao S, Shin T, et aL Interacton between B7- H1 and PD-1 determines initiation and reversal of T-cell anergy [ J ]. Blood,2007,110 ( 1 ) :180-185.
  • 7Keir ME, Butte MJ, Freeman GJ, et al. PD-1 and its ligands in tolerance and immunity [ J ]. Annu Rev Immunol, 2008,26:677-704.
  • 8丁庆,路丽明,周芸,辛利军,江阳,焦志军,周晓荣,周光炎.小鼠B7H1-Ig融合蛋白诱导免疫抑制的机制研究[J].现代免疫学,2006,26(2):93-97. 被引量：6
  • 9刘书漫,刘国红,张钦宪,刘占举.B7-H1在结肠癌组织中的表达及意义[J].世界华人消化杂志,2009,17(8):841-843. 被引量：7
  • 10柯尊金,曾甫清,朱伟.膀胱癌组织中程序性死亡配体-1的表达及其意义[J].临床泌尿外科杂志,2007,22(1):54-56. 被引量：2

二级参考文献30

  • 1王莉娟,王贵吉,牛虹,邢鑫.结肠癌组织中趋化因子受体CXCR4和基质金属蛋白酶MMP-2的表达及意义[J].肿瘤基础与临床,2007,20(2):134-136. 被引量：5
  • 2Dong H, Strome SE, Salomao DR, et al. Tumor-associated B7-HI promotes T-cell apoptosis: a potential mechanism of immune evasion. Nat Med, 2002, 8:793-800.
  • 3Strome SE, Dong H, Tamura H, et al. BT-HI blockade auguments adoptive T-cell immunotherapy for squamous cell carcinoma, Cancer Res, 2003, 63:6501-6505.
  • 4Konishi J, Yamazaki K, Azuma M, et al. B7-H1 expression on non-small cell lung cancer cells and its relationship with tumorinfiltrating lymphocytes and their PD-1 expression. Clin Cancer Res, 2004, 10:5094-5100.
  • 5Ohigashil Y, Sho M, Yamada Y, et al. Clinical significance of programmed death-1 ligand-1 and programmed death-1 ligand-2 expression in human esophageal cancer. Clin Cancer Res, 2005, 11:2947-2953.
  • 6Nomi T, Sho M, Akahori T, et al. Clinical significance and therapeutic potential of the programmed death-1 ligand/programmed death-1 pathway in human pancreatic cancer. Clin Cancer Res, 2007, 13 : 2151-2157.
  • 7Cho Y, Miyamoto M, Kato K, et al. CD4^+ and CD8^+ T cells cooperate to improve prognosis of patients with esophageal squamous cell carcinoma. Cancer Res, 2003, 63 : 1555-1559.
  • 8Ropponen KM, Eskelinen MJ, Lipponen PK, et al. Prognostic value of tumour-infiltrating lymphocytes (TILs) in colorectal cancer. J Pathol, 1997, 182:318-324.
  • 9Greenwald RJ, Freeman GJ, Sharpe AH. The B7 family revisited. Annu Rev Immunol, 2005, 23:515-548.
  • 10Dong H, Zhu G, Tamada K, et al. B7-H1 ,a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion. Nat Med, 1999, 5:1365-1369.

共引文献38

同被引文献11

  • 1杨星,李力人,潘志忠,周志伟,万德森.Dukes’B期直肠癌微淋巴管密度检测及其临床意义[J].癌症,2006,25(6):749-752. 被引量：3
  • 2Bretscher P,Cohn M. A theory of self-nonself discrimina-tion:paralysis and induction involve the recognition of one and two determinants on an antigen,respectively[J].Science,1970,(950):1042-1049.
  • 3Dong HD,Strome SE,Salomao DR. T umor-associat-ed B7-H1 promotes T-cell apopt-osis:a potential mecha-nism of immune evasion[J].Nature Medicine,2002,(08):793-800.
  • 4Pardoll DM. Spinning molecular immunology into succes-ful immunotherapy[J].Nature Reviews Immunology,2002,(04):227-238.
  • 5Dong H,Strome SE,SalomaoDR. Tumor associated B7-1 promotes T-cell apoptosis:a potential mechanism of immune evasion[J].Nature Medicine,2002,(08):793-800.
  • 6Brown JA,Dorfman DM,Ma FR. Blockade ofpro-grammed death-1 ligands on dendritic cells enhances T cell activation and cytokine production[J].Journal of Immunology,2003,(03):1257-l266.
  • 7Konishi J,Yamazaki K,Azuma M. B7-H1 expression on non-small cell lung cancer cells and its relationship with tumor-infiltrating lymphoeytes and their PD-1 expres-sion[J].Clinical Cancer Research,2004,(15):5094-5100.
  • 8Curiel TJ,Wei S,Dong H. Blockade of B7-H1 im-proves myeloid dendritic cell-mediated antitumor immuni-ty[J].Nature Medicine,2003,(05):562-567.doi:10.1038/nm863.
  • 9Yoshiko I,Masayoshi I,Yoshimasa T. Involvement of PD-L1 on tumor cells in the escape from host immun system and tumor immunotherapy by PD-L1 blockade[J].Proceedings of the National Academy of Sciences(USA),2002,(19):12293-12297.
  • 10刘书漫,刘国红,张钦宪,刘占举.B7-H1在结肠癌组织中的表达及意义[J].世界华人消化杂志,2009,17(8):841-843. 被引量：7

引证文献1

二级引证文献2

中国临床保健杂志
2013年 第2期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部