抗菌药物临床应用干预管理

Clinical Application of Antibiotics Intervention Anagement

目的:运用综合干预措施对临床使用抗菌药物进行管理。方法:选择住院患者抗菌药物用药频度(DDDs)、住院患者抗菌药物使用率等指标对2011～2012年住院患者抗菌药物使用情况进行调查。结果:住院患者抗菌药物使用强度从2011年第一季度74DDD下降到2012年第四季度38DDD,住院患者抗菌药物使用率从2011年第一季度75.7%下降到2012年第四季度35.3%,其中Ⅰ类切口预防用抗菌药物从2011年第一季度68.1%下降到2012年第四季度19%,差异有统计学意义。结论:通过有效的干预措施,我院抗菌药物临床应用各项指标均达到国家要求。

Objective： Using comprehensive intervention measures to supervise and control the clinical use of antibiotics. Methods： As the frequency and rate of antibiotics （defined daily doses） usage like index to investigate the antibiotics use in hospitalized patients from 2011 to 2012. Results： Among 2011 to 2012 in hospitalized patients,antibiotics use density was decreased from 74DDD to 38DDD, and the rates of antibiotics usage were fell from 75. 7% to 35. 3% ,in which usage of antibiotics to prevention on typeⅠ incision were decreased from 68. 1% to 19% ,all of these show statistically significant difference. Conclusion： Adopting effective intervention measures to administration of antibiotics in clinical usage,can make all indexes meet the national requirements.