期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

FISH技术在肿瘤分子诊断中的应用

下载PDF
导出
摘要 荧光原位杂交（fluorescence in situ hybridization,FISH）是20世纪80年代末在放射性原位杂交技术的基础上发展起来的一种非放射性分子细胞遗传技术。因其具有快速、安全、灵敏度高及探针可长期保存等优点,目前已广泛应用于细胞遗传学、肿瘤生物学和产前诊断等领域,尤其在肿瘤筛查、早期诊断及指导临床用药方面具有很好的应用价值。
作者 宋秀军 吕进 江其生
机构地区 第二炮兵总医院中心实验室
出处 《放射免疫学杂志》 CAS 2013年第4期426-428,共3页 Journal of Radioimmanology
关键词 肿瘤生物学 FISH技术 应用 分子诊断 荧光原位杂交 原位杂交技术 非放射性 细胞遗传学
分类号 R735.2 [医药卫生—肿瘤]
  • 相关文献

参考文献18

  • 1Hagemeijer A, de Klein A, Godde - Salz E, et al. Translocationof c-abl to " masked" Ph in chronic myeloid leukemiaf J] . Cancer GenetCytogenet, 1985,18(2) :95-104.
  • 2Smoley SA, Brockman SR, Paternoster SF, et al. A novel tricolor,dual-fusion fluorescence in situ hybridization method to detect BCR/ABLfusion in cells with t (9;22 ) ( q34; qll. 2 ) associated with deletion ofDNA on the derivative chromosome 9 in chronic myelocytic leukemia[ J].Cancer Genet Cytogenet,2004,148 (1) :1-6.
  • 3Kim KE, Woo KS, Kim SH,et al. Detection of PML/RARA rear-rangement by reverse transcriptase-PCR and sequencing in a case of mi-crogrannlar acute promyelocytic leukemia lacking t( 15 ; 17) on karyotypeand FISH[J]. Korean J Lab Med, 2009,29(5) : 379-383.
  • 4Polampalli S, Choughule A, Prabhash K, et al. Role of RT-PCRand FISH in diagnosis and monitoring of acute promyelocytic leukemia[J]. Indian J Cancer, 2011, 48(1) : 60-67.
  • 5Baro C, Espinet B, Salido M,et al. Cryptic IGH/BCL2 rearrange-ments with variant FISH patterns in follicular lymphoma [ J ]. Leuk Res,2011,35(2): 256-259.
  • 6Mulligan S, Hu P, Murphy A,et al. Variations in MALT1 genedisruptions detected by FISH in 109 MALT lymphomas occurring in differ-ent primary sites [J]. J Assoc Genet Technol, 2011,37(2) : 76-79.
  • 7Chang CM, Schroeder JC, Huang WY, et al. Non-Hodgkin lym-phoma (NHL) subtypes defined by common translocations : utility of fluo-rescence in situ hybridization (FISH) in a case-control study[ J]. LeukRes, 2010, 34(2): 190-195.
  • 8韩静静,李海刚,曾韵洁,沈溪明,范苗静,郑娜芬.乳腺癌中HER-2基因的扩增及意义[J].岭南现代临床外科,2011,11(3):171-173. 被引量：4
  • 9Weaver DT, Pierceall W, Sprott KM, et al. Top2A FISH with cy-tokeratin discriminators in breast cancer using automated hi^hi throughputanalysisfj]. ASCO Meeting Abstracts, 2010, 28: ell061.
  • 10Bravaccini Sara, Rengucci Claudia, Medri Laura?et al. Detectionof HER2 and Topo 2 in breast cancers : comparison between MLPA andFISH approaches[ J]. J Clin Pathol, 2012,65(2) : 183-185.

二级参考文献8

  • 1Paula J. Whittington,Olga Radkevich-Brown,Jennifer B. Jacob,Richard F. Jones,Amy M. Weise,Wei-Zen Wei.Her-2 DNA versus cell vaccine: immunogenicity and anti-tumor activity[J]. Cancer Immunology, Immunotherapy . 2009 (5)
  • 2Bianchini G,,Iwamoto T,Qi Y,et al.Prognostic and therapeutic im-plications of distinct kinase expression patterns in different subtypes ofbreast cancer. Cancer Research . 2010
  • 3Egervari K,Szollosi Z,Nemes Z.Immunohistochemical antibodies in breast cancer HER2 diagnositics.A comparative immunohistochemical and fluorescence in situ hybridization study. Tumour Biology . 2008
  • 4Xu ZH,Ford BD.Upregu lation of ErbB receptors in rat brain afterm idd le cerebral arterial occlusion. Neuroscience Letters . 2005
  • 5Singletary SE,Allred C,Ashley P,et al.Staging system for breast cancer:revisions for the 6th edition of the A- JCC Cancer Staging Manual. Surgical Oncology Clinics of North America . 2003
  • 6Hicks DG,Tubbs RR.Assessment of the HER2 status in breast cancer by fluorescence in situ hybridization: a technical review with interpretive guidelines. Human Pathology . 2005
  • 7Press MF,Slamon DJ,Flom KJ,et al.Evaluation of HER-2/neu gene amplification and overexpression: comparison of frequently used assay methods in a molecularly characterized cohort of breast cancer specimens. Journal of Clinical Oncology . 2002
  • 8Engel RH,Kaklammi VG,李冬梅,吕娟丽,何慧丽.HER2阳性乳腺癌的治疗策略[J].国际药学研究杂志,2008,35(4):288-290. 被引量：3

共引文献3

放射免疫学杂志
2013年 第4期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部