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microRNA与肿瘤发生的关系及在临床诊治中应用 被引量：5

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摘要 microRNA(miRNA)是一类内源性非编码小分子RNA,通过阻遏mRNA的翻译来调控基因的表达,大量研究证明其与肿瘤的发生密切相关。该文将重点论述调控肿瘤发生、发展的miRNA,详细阐述这些短片段RNA在肿瘤的分子诊断及临床个体性治疗中的应用。
作者 赵苏苏 余泽前 王露 李惠 张树鹏 赖仁胜
机构地区 南京中医药大学附属医院病理科/国家中管局三级分子生物实验室 东南大学附属中大医院普外科
出处 《临床与实验病理学杂志》 CAS CSCD 北大核心 2013年第7期779-782,共4页 Chinese Journal of Clinical and Experimental Pathology
基金 江苏高校优势学科建设工程资助(012062003010)
关键词 MICRORNA 肿瘤发生 预后 诊断 治疗 文献综述
分类号 R730.231 [医药卫生—肿瘤]
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参考文献29

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同被引文献40

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临床与实验病理学杂志
2013年 第7期

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