核素骨显像诊断分化型甲状腺癌转移灶的应用价值

Application of Radionuclide Bone Imaging in Diagnosis of Differentiated Thyroid Carcinoma Metastases

目的探讨核素骨显像对分化型甲状腺癌骨转移的临床诊断价值。方法对35例分化型甲状腺癌骨转移癌患者99mTc-MDP全身骨显像结果进行回顾性分析。结果多发骨转移(82.86%)明显多于单发骨转移(17.14%);转移灶的分布规律是躯干骨多于四肢骨和颅骨;多数病人有骨痛症状。结论核素骨显像对甲状腺癌骨转移诊断具有较高的敏感性,联合MRI、PET-CT及X射线平片检查更能提高诊断准确率。

Objective To evaluate the clinical effectiveness of radionuclide bone imaging in diagnosis of bone metastasis of differentiated thyroid carcinoma.Methods An examination of 35 patients who suffered from differentiated thyroid carcinoma with bone metastasis was performed with 99mTc-MDP radionuclide bone imaging.The results were retrospectively analyzed.Results Occurrences of multiple bone metastases（82.86%） were observed more than those of single bone metastases（17.14%）.Metastases were found to be distributed in trunk bones more than limb bones and skulls.The symptom of pain appeared in the majority of patients.Conclusion Radionuclide bone imaging showed a high sensitivity in diagnosis of bone metastases.Combining radionudide bone imaging with MRI（magnetic resonance imaging）,PET-CT（positron emission tomography-computed tomography） and X-ray examination,a highly-enhanced accuracy in diagnosis would be achieved.