祛痰化瘀中药干预冠心病稳定型心绞痛痰瘀互结证临床观察

Clinical Observation of Quality of Life in Patients with Coronary Heart Disease Treated by Eliminating Phlegm and Resolving Stasis

目的:探究祛痰化瘀法干预冠心病稳定型心绞痛痰瘀互结患者的临床疗效观察。方法:将240例冠心病稳定型心绞痛痰瘀互结证患者随机分为试验组、对照组,试验组采用西医基础治疗结合祛痰化瘀中药辨证加减,对照组采用西医基础治疗结合中药安慰剂,疗程为8周,以心电图变化、西雅图心绞痛量表(SAQ)评定治疗先后的疗效。结果:治疗后,两组心电图各导联ST段下降值总和,试验组较对照组改善明显,两者比较有统计学意义(P<0.05);SAQ评价方面,试验组、对照组治疗后较治疗前均有好转,治疗后试验组较对照组相比,患者躯体活动受限程度、疾病认识程度、总分面改善效果相对明显。结论:祛痰化瘀中药能改善冠心病心绞痛患者的整体生活质量,且辨证用药又具有明显的优越性。

Objective： To explore the clinical efficacy of stable angina patients with phlegm and blood intervened by the method of eliminating phlegm and resolving stasis.Methods： 240 stable angina patients with phlegm and blood were randomly divided into test group and control group.The test group used basic Western medical therapy combined with method of eliminating phlegm and resolving stasis.The control group used basic Western medical therapy combined with traditional Chinese medicine functioning as comfort agent for eight weeks.ECG changes and the Seattle Angina Questionnaire（SAQ） were used to assess the treatment efficacy.Results： After treatment,the total decline of ST-segment in ECG in the experimental group was much better compared with the control group,which had statistical significance（P0.05）.On the aspect of SAQ evaluation,both of the test and control groups were improved after treatment.Patients＇ limitation of body activities,awareness of disease,and improvement of total score in experimental group were improved obviously than those in the control group after treatment.Conclusion： Eliminating phlegm and resolving stasis Chinese medicine can improve the quality of life in patients with angina pectoris and TCM drugs have obvious advantages.