丹参注射液对病毒性心肌炎的临床诊治效果分析

Clinical Observation on Effect of Salvia Injection on Viral Myocarditis

目的:考察丹参注射液对于临床病毒性心肌炎的治疗效果,并分析其可能的。方法:选取我院收治患者72例,其中男38例,女34例,平均年龄为(22.98±8.26)岁,患者被随机分为治疗组和对照组,对照组只接受基础治疗,治疗组在基础治疗的基础上采用丹参注射液治疗。治疗结束后,检测患者心肌酶、TNF-α和IL-2、并记录不同组别的治愈率。结果:对照组患者36例,治愈14例(39.0%),显效11例(30.5%),无效11例(30.5%)。治疗组患者36例,治愈21例(58.3%),显效12例(33.3%),无效3例(8.4%);两组血清中TNF-α,IL-2含量均较治疗前明显降低(P<0.01),而治疗组降低程度优于对照组(P<0.01);治疗后CPK、AST、LDH、CK-MB治疗组优于对照组(P<0.05)。结论:丹参注射液联合应用可有效的治疗病毒性心肌炎,其机制可能与丹参的抗炎、降低心肌酶作用有关。

Objective：To investigate the effect of Salvia Injection on viral myocarditis.Methods：72cases,including 38 male cases,34 female cases,with an average age of（22.98±8.26） years old,were randomly divided into treatment group and control group.The control group only accepted foundation treatment;the treatment group added Salvia Injection.After treatment,myocardial enzyme,TNF alpha and IL-2 were detected,and the cure rates of two groups were recorded.Results：In control group,14 cases（39.0%） were cured,11 cases（30.5%） effective,8 cases（30.5%） invalid.In the treatment group,21 cases（58.3%） were cured,12 cases（33.3%） effective,3 cases（8.4%） invalid.TNF alpha and IL-2 contents in serum were reduced significantly（P〈0.01）,and the reduced degree in treatment group was superior to that in control group（P〈0.01）.After treatment,CPK,AST and LDH and CK-MB in the treatment group had a greater reduce than those in control group（P〈0.05）.Conclusion：Salvia Injection can be effective in the treatment of viral myocarditis,and the mechanism may be related to anti-inflammatory as well as reducing cardiac enzymes.