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巨噬细胞在脓毒症中的免疫调节作用研究进展 被引量：4

Research progress in immunoregulatory role of macrophages in sepsis
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摘要 巨噬细胞作为脓毒症中天然免疫反应中的抗感染细胞及特异性免疫中的关键抗原呈递细胞,其功能变化在脓毒症中的作用受到人们的特别关注。该文综述了巨噬细胞在脓毒症中的免疫调节作用研究进展。 Macrophages are anti-infected cells in the innate immune response in sepsis,and are critical antigen-presenting cells in specific immune.So their changes of function in sepsis are of particular concern.This paper reviews the immunoregulatory function changes of the macrophages in sepsis.
作者 杨小梅 韩根成 马远方 黎燕
机构地区 河南大学医学院免疫学研究所 军事医学科学院基础医学研究所分子免疫学研究室
出处 《军事医学》 CAS CSCD 北大核心 2013年第6期469-471,共3页 Military Medical Sciences
基金 国家自然科学基金资助项目(81072475) 国家973计划资助项目(2007CB512406)
关键词 脓毒症 巨噬细胞 免疫调节 sepsis macrophage immune regulation
分类号 R459.7 [医药卫生—急诊医学]
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参考文献19

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同被引文献59

  • 1刘晓蓉,任新生.脓毒症凝血机制及组织因子通路抑制剂治疗的研究现状及治疗进展[J].中国急救医学,2005,25(11):833-835. 被引量：19
  • 2魏芳,王立华,姜埃利.脓毒血症与内皮细胞功能异常[J].国际移植与血液净化杂志,2006,4(5):9-12. 被引量：2
  • 3吴健,李澎,陈卫民.血清C反应蛋白水平预测危重症患者预后的临床研究[J].中国医科大学学报,2007,36(3):358-358. 被引量：11
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  • 6Dellinger RP’Levy MM,Rhodes A,et al. Surviving sepsiscampaign: International guidelines for management of se-vere sepsis and septic shock: 2012 [J]. Crit Care Med,2013,41:580-637.
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  • 8Heper Y, Akalin EH,Mistik R,et al. Evaluation of serumC-reactive protein, procalcitonin, tumor necrosis factor al-pha, and interleukin-10 levels as diagnostic and p- rognos-tic parameters in patients with community-acquired sep-sis, severe sepsis,and septic shock[J]. Eur J Clin Microbi-ol Infect Dis,2006,25(8) :481-491.
  • 9Takahashi N, Hasegawa H, Komiyama M, et al. Electiveexcretion of anti-inflammatory cytokine interleukin-10 in asuperantigen-inducing neonatal infectious disease [J]. Cy-tokine, 2009 ,45(1) : 39-43.
  • 10Santana Reyes C,Garcia-Muoz F.Reyes D, et al. Role ofcytokines (interleukin-1 beta,6,8,tumor necrosis factor-a, and soluble receptor of interleukin-2) and C-reactiveprotein in the diagnosis of neonatal sepsis[J], Acta Paedi-atr,2003,92(3):221-227.

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二级引证文献10

军事医学
2013年 第6期

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