茵栀黄口服液灌肠预防早产儿喂养不耐受临床观察

Clinical observation on enema with Yinzhihuang oral liquid to prevent feeding intolerance of premature infants

目的观察茵栀黄口服液灌肠预防早产儿喂养不耐受的临床效果。方法将98例早产儿随机分为干预组和对照组，每组49例，对照组仅给予早期干预治疗，干预组在早期干预的同时给予茵栀黄口服液灌肠；比较两组治疗后胎便排净、腹胀消失、呕吐缓解、恢复至出生体重、达到全肠道喂养的时间。结果干预组在首次排胎便、胎便排净、腹胀消失、呕吐缓解、恢复至出生体重及达到全胃肠喂养的时间明显短，与对照组比较差异均有统计学意义（t值分别为1．443、2．568、1．512、2．791、2．011、4．189，均P〈0．05）。结论茵栀黄口服液灌肠治疗早产儿喂养不耐受效果显著，可减少早产儿喂养不耐受的发生。

Objective To observe the clinical efficacy of enema with Yinzhihuang oral liquid to prevent feeding intolerance of premature infants. Methods A total of 98 preterm infants were randomly divided into intervention group and control group with 49 cases in each group. Control group was given early intervention treatment only, while intervention group was given enema treatment with Yinzhihuang oral liquid based on early intervention. The time of complete exhaust of meconium, disappearing of distention, relieving of vomiting, coming to birth weight and getting full enteral feeding were compared between two groups. Results The time of first exhaust of meconium, complete exhaust of meconium, disappearing of distention, relieving of vomiting, coming to birth weight and getting full enteral feeding was obviously shortened in intervention group, and the differences were significant when compared to control group （t value was 1. 443, 2.568, 1. 512, 2.791, 2. 011 and 4. 189, respectively, all P 〈 0. 05）. Conclusion The effect of enema with Yinzhihuang oral liquid on feeding intolerance of premature infants is significant, and the incidence of feeding intolerance of premature infants can be reduced.