1,3,4-噁二唑的酰基硫脲衍生物的合成

Synthesis of N'-(5-aryl-1,3,4-oxadiazol-2-yl)phenoxyacetylthioureas

从邻氯苯酚出发合成邻氯苯氧乙酰异硫氰酸酯 ,分别与 5种 2 -氨基 -5-芳基 -1 ,3 ,4 -口恶二唑反应得到 1 ,3 ,4 -口恶二唑的邻氯苯氧乙酰基硫脲衍生物 ,用 IR,1 H NMR,元素分析等对它们的结构进行了确证 ,并分析归纳合成该目标产物的最佳合成条件 .

A series of N (5 aryl 1,3,4 oxadiazol 2 yl)phenoxyacetylthioureas are synthesized from 2 amino 5 aryl 1,3,4 oxdiazoles.All of them are new compounds.Their structures have been confirmed by IR, 1H NMR and elementary analysis and the best reaction conditions have been compared and analysed.