T波电交替预测法洛四联症术后室性心律失常的价值

The value of T wave alternans in prediction of ventricular arrhythmias in post-op TOF children

目的探讨T波电交替(TWA)预测法洛四联症(TOF)术后室性心律失常的价值。方法回顾性分析36例TOF术后儿童及120例年龄相仿正常儿童的TWA特点及持续TWA与室性心律失常发生的关系。结果 TOF术后患儿持续TWA发生率(36.1%)明显高于正常对照儿童(15.8%),差异有统计学意义(χ2=6.98,P<0.05);TOF术后出现持续性TWA患儿在运动过程中室性心律失常的发生率(76.9%)远高于TOF术后无持续TWA患儿(21.7%),差异有统计学意义(χ2=10.41,P<0.05)。结论 TOF术后患儿存在发生室性心律失常的电生理基础,持续TWA对预测TOF术后室性心律失常具有重要价值。

Objective To explore the value of T wave alternans （TWA） in prediction ventricular arrhythmias in post-op TOF children. Methods The characteristics of TWA were retrospectively analyzed in 36 post-op TOF patients and 120 age- matched normal children. The relationship of sustained TWA and ventricular arrhythmias was also analysed. Results Compared with normal children, the incidence of sustained TWA was significantly increased in post-op TOF group （3~=6.98, P〈0.05）. In post-op TOF patients, the incidence of ventricular arrhythmia was much higher when sustained TWA was present （23=10.41, P〈0.05）. Conclusions There exists electrophysiological basis for ventricular arrhythmia in post-op TOF children. Sustained TWA has important value in prediction of ventricular arrhythmia of post-op TOE