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参芪扶正注射液联合环磷腺苷葡胺对慢性心功能不全心脏功能及BNP的影响 被引量:1

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摘要 目的:观察参芪扶正注射液联合环磷腺苷葡胺对慢性心功能不全患者BNP及心功能的影响。方法:选择CHF患者100例,随机分为治疗组与对照组,每组50例,治疗组给予参芪扶正注射液注射液250 ml,静脉滴注1次/d,环磷腺苷葡胺120 mg静脉滴注,1次/d,以及吸氧、洋地黄、利尿剂、血管紧张素转换酶抑制剂、硝酸酯类等药物等抗心力衰竭治疗。对照组予以吸氧、洋地黄、利尿剂、血管紧张素转换酶抑制剂、硝酸酯类等药物等基础性治疗,疗程均为2周。治疗前后均测定血浆BNP浓度、左室射血分数,观察治疗前后两组心功能和血B型钠尿肽的变化和组间差异。结果:治疗组对心力衰竭的临床疗效优于对照组(P<0.01);两组患者治疗后血B型钠尿肽水平较治疗前均明显下降(P<0.01),但两组间差异有统计学意义(P<0.01)。结论:慢性心力衰竭患者在常规治疗基础上加用参芪扶正注射液及环磷腺苷葡胺治疗可进一步改善心功能,降低血浆B型钠尿肽水平。
作者 张丹
出处 《吉林医学》 CAS 2013年第21期4272-4273,共2页 Jilin Medical Journal
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