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hs-CRP和血小板参数与心衰患者病情严重程度的关系 被引量:15

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摘要 目的探讨心衰患者高敏C反应蛋白hs-CRP和血小板参数与患者病情严重程度的相关性。方法检测760例心衰患者的hs-CRP、血小板计数(PLT)、平均血小板体积(MPV)、血小板体积分布宽度(PDW)和大血小板比率(P-LCR),将患者按不同分组进行分析。结果 hs-CRP水平随心功能分级增加而增加(P<0.001)。PLT随心功能分级增加而降低,MPV、PDW和P-LCR随心功能分级增加而增加(P<0.001)。将患者按心衰的病因分组,hs-CRP水平在各种心衰病因中无差异(P=0.123),PLT、MPV、PDW和P-LCR在各种病因中均有差异(P<0.01);心衰患者NT-proB-NP水平与hs-CRP呈正相关(r=0.289,P<0.001),与PLT(r=-0.139,P=0.001)呈负相关,与MPV(r=0.246,P<0.001)、PDW(r=0.213,P<0.001)和P-LCR(r=0.247,P<0.001)均呈正相关。结论心衰患者hs-CRP和血小板参数与病情严重程度密切相关,检测这些指标有助于患者的病情评估和疗效监测。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2013年第14期3320-3322,共3页 Chinese Journal of Gerontology
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