期刊文献+

雌激素与基质金属蛋白酶(MMPs) 被引量:1

Estrogen and matrix metalloproteinase(MMPs)
下载PDF
导出
摘要 雌激素对基质金属蛋白酶的影响十分复杂,不同的组织细胞中在不同的环境下,对不同基质金属蛋白酶的作用有抑制和活化两方面效应。另外,雌激素对基质金属蛋白酶的影响还分别体现在信使RNA、蛋白的表达和活化等不同层次。 Research has shown that the effect of estrogen on matrix metalloproteinase is very complicated. For ex- ample, the influence on different matrix metalloproteinases under different circumstances in different histiocytes is quite variabe. In addition, the effects can be observed on the levels of messenger RNA and the expression or the activation of proteins.
出处 《基础医学与临床》 CSCD 北大核心 2013年第8期1059-1062,共4页 Basic and Clinical Medicine
基金 吉林省自然科学基金(201215001)
关键词 雌激素 基质金属蛋白酶 抑制 活化 estrogen matrix metalloproteinase inhibition/activation
  • 相关文献

参考文献15

  • 1Back M,Ketelhuth DF,Agewall S. Matrix metalloproteinasesin atherothrombosi [ J ]. Prog Cardiovasc Dis, 2010, 52:410-428.
  • 2Li X,Wu JF. Recent developments in patent anti-cancer a-gents targeting the matrix metalloproteinases ( MMPs ) [ J ].Recent PatAnticancer Drug Discov,2010,5 : 109 - 141.
  • 3Hawinkels LJ,Kuiper P,Wiercinska E,et al. Matrix metal-loproteinase-14-mediated endoglin shedding inhibits tumorangiogenesis[ J]. Cancer Res,2010,70: 4141 -4150.
  • 4Schuliga M, Ong SC, Soon L^et al. Airway smooth muscleremodels pericellular collagen fibrils : implications for prolif-eration [J ]. Am J Physiol Lung Cell Mol Physiol, 2010,298 :L584 -L592.
  • 5Sp6nikov6 A,Ivanovd M,Matejlkova J,et al. Influence of is-chemia / reperfusion and modulation of PI3K / Akt kinasepathway on matrix metalloproteinase-2 in rat hearts[ J]. GenPhysiol Biophys,2010,29: 31 -40.
  • 6Wang K,Lin YF,Qin CH, et al. Bisphenol-A interfereswith estradiol-mediated protection in osteoarthritic chondro-cytes [J]. Toxicology Lett, 2012, 198: 127 -133.
  • 7Horst C, Reinhard S,Joachim H, et al. 17p-estradiol re-duces expression of MMP-1 ,-3 , and-13 in human primaryarticular chondrocytes from female patients cultured in athree dimensional alginate system [ J ]. Cell Tissue Res,2010,342: 283 -293.
  • 8Braundmeier AG, Fazleabas AT,Nowak RA. Extracellularmatrix metalloproteinase inducer expression in the baboonendometrium : menstrual cycle and endometriosis [ J ]. Re-production ,2010,140 : 911 -920.
  • 9Claudia Z, Vanessa S, Olga P, et al. Estrogen up-regula-tion of metalloproteinase-2 and-9 expression in rabbit lacri-mal glands[ J]. Exp Eye Res, 2007 , 84: 960 -972.
  • 10Sara M, Maria AS. Estrogen activates matrix metallopro-teinases-2 and-9 to increase beta amyloid degradation[ J].Mol Cell Neurosci, 2012 , 49 : 423 - 429.

同被引文献46

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部