肛肠病人术后应用奥硝唑预防感染的临床研究

Plateau Region Anorectal Disease after Surgery Using Ornidazole of 180 cases of Patients Randomized Controlled Study

目的:观察在肛肠手术后应用奥硝唑预防术后感染的时效。方法:采用随机、双盲和对照的方法,对180例痔疮术后患者,内痔采用单纯结扎术;血栓性外痔采用剥离摘除术,结缔组织性外痔采用切除术,静脉曲张性外痔采用剥离切除术;混合痔采用外剥内扎术[1];全部手术均采用局部浸润麻醉。术后患者按连续使用奥硝唑的时间随机分为3天组、7天组和10天组。比较三组术后感染的恢复情况。结果:7天组在术后感染的控制明显优于3天组,其差异具有统计学意义;10天组与7天组术后感染无显著性差异,差异无统计学意义。用药期间未见不良反应发生。结论:痔疮手术后连续7天使用奥硝唑可以较好的控制术后感染。

Objective To observe after anorectal surgery using Austrian metronidazole how many days is the most effective prevention to postoperative infection. Methods Using randomized, double-blind and Comparison method, 180 cases of patients of hemorrhoids surgery, the internal hemorrhoids simple ligation ; thrombotic external hemorrhoids peel excision, resection of connective tissue exter- nal hemorrhoids, varicose veins peel resection; the mixed hemorrhoids Milligan surgery; All operations were performed using local an- esthesia. Results 7 days group postoperative infection control significantly better than the 3 - day group, the difference was statistically significant ; 10 days group and 7 days group postoperative infection was no significant difference, the difference was not statistically significant. During the treatment, the three groups had no significant toxicity occurred. Conclusion After hemorrhoids surgery continuous use Ornidazole for 7 clays can better control postoperative infection.