足月儿患呼吸窘迫综合症产科风险因素的研究

The Research of obstetric risk factors of full -term children suffering from respiratory distress syndrome

目的:本研究的目的是调查在妊娠期的第37周和42周之间足月儿患上呼吸窘迫综合症(RDS)的产科风险因素。方法:回顾性的研究了70个患有呼吸窘迫综合症的足月儿,这些足月儿来自甘肃省妇幼保健院,时间是行2002年1月到2010年12月。随机选择了142个健康的足月儿作为对照组。调查了母亲的社会人口特点,分娩历史,主要的并发症,临床处理和分娩的模式。结果:足月儿患有吸窘迫综合症的发生率是1.2‰。比较了患有吸窘迫综合症的实验组足月儿(n=70)与不患有吸窘迫综合症的对照组足月儿(n=142)的分娩的影响因素表明:妊娠期糖尿病(11.43%/1.41%;P=0.027),子痫前期(14.29%/1.41%;P=0.024),男婴(74.29%/25.71%;P=0.04)和剖宫产分娩(60%/30.99%;P=0.001)在对照组明显较高。然而,其它的产科因素,例如母亲的年龄,经产状况,母性的物质暴露,贫血症,糖尿,妊娠期高血压,阴道感染,保胎,羊水过少,在两组之间并没有显著差异。结论:妊娠期糖尿病,子痫前期,男婴和剖宫产分娩似乎是妊娠期的足月儿患上呼吸窘迫综合症的产科风险因素。

Objective：The purpose of this study was to investigate obstetric risk factors of full-term infant between 37 and 42 weeks of pregnancy suffering from respiratory distress syndrome. Methods：A retrospective study of 70 full-term infant with respiratory distress syndrome, these infants from the Maternity and Child-care Hospital of Gansu Province between January 2002 to December 2010. Randomly selected 142 healthy full-term infants as a control group. Investigated these mothers＇ socio-demographic characteristics, birth history,major complications, clinical treatment and delivery modes. Results：The incidence of the full-term infants suffering from distress syndrome is one point two out of one thousand （1.2‰）. Compared with full-term infants suffering from respiratory distress syndrome in the experimental group （n=70） and not suffering distress syndrome term infants in the control group （n=142）showed that the influencing factors of birth：gestational diabetes （11.43%/1.41%;P=0.027）,preeclampsia （14.29%/1.41%;P=0.024）,boys （74.29%/25.71%;P=0.04）and cesarean delivery （60%/30.99%;P=0.001）was significantly higher in the control group. However,other obstetric factors,such as mother＇s age,the production conditions,maternal substance exposure,anemia,diabetes,gestational hypertension,vaginal infection,miscarriage,oligohydramnios, between the two groups and no significant differences. Conclusion：gestational diabetes,preeclampsia,boy and cesarean delivery seem to be full-term pregnancy respiratory distress syndrome in children suffering from obstetric risk factors.