解脲支原体感染、精浆锌与男性不育患者精子形态的关系

Relationship between ureaplasma urealyticum infection,seminal plasma zinc and sperm morphology of infertile men

目的探讨男性不育患者解脲支原体感染、精浆锌与精子形态的关系。方法对1071例男性不育患者进行解脲支原体、精浆锌含量和精子形态的检测后，按是否感染解脲支原体分为感染组和未感染组，对比两组精浆锌水平，再将其细分为精浆锌正常组和异常组，在组与组之间分别对比正常精子形态百分率。结果解脲支原体感染组（117例）平均精浆锌的含量（1.63±0.34）μmol/L低于未感染组（954例）（2.47±0.38）μmol/L，两组差异有统计学意义（P＜0.05）。感染组正常精子形态百分率（12.21±4.92）%，显著低于未感染组（18.65±8.11）%。感染组中精浆锌异常组的形态百分率（8.71±3.51）%，低于精浆锌正常组（11.3±7.12）%（P＜0.05），同时也低于未感染组中的精浆锌异常组（16.60±9.05）%（P＜0.05）。未感染组中，精浆锌异常组的正常精子形态百分率与精浆锌正常组相比差异无统计学意义（P＞0.05）。结论解脲支原体感染对男性不育患者的精子形态学有较大影响，需及时治疗。精浆锌对精子形态学的影响受其他因素的制约，但也应给予重视。

Objective To study the relationship between ureaplasma urealyticum（UU） infection,seminal plasma zinc and sperm morphology. Methods UU infection, seminal plasma zinc level and sperm morphology were dectected in 1071 male infertile patients. Results Seminal plasma zinc concentration in UU positive group was low than that in UU negative group（P〈0.05）. In UU positive group ,the number of normal morphologic sperm in abnormal zinc concentration group was lower than that in normal zinc concentration group（P〈0.05）, and in abnormal zinc concentration group of UU negative group（P〈0.05） respectively. There was no significant difference in the proportion of normal morphologic sperm between abnormal zinc concentration group and normal zinc concentration group in UU negative group（P〉0.05）. Conclusion UU infection might affect sperm morphology of male infertility. Effect of seminal plasma zinc level on sperm morphology was easily changed by other complication, but this change should drive our attention.