经颅多普勒在儿童偏头痛诊断中的应用

Application of Transcranial Doppler in Diagnosis of Child Migraine

目的探讨经颅多普勒(TCD)在儿童偏头痛发作时所测定的颅底血管血流动力学的改变。分析儿童偏头痛的TCD特征、临床特点及治疗转归,提高对此病的认识。方法采用经颅多普勒(TCD)测量30例正常儿童的脑血管血流速度。同时对68例儿童偏头痛发作时颅内各血管的血流速度进行回顾性分析,将采集的数据储存于电脑中,进行频谱处理分析,再根据收缩期和舒张期流速自动分析得出平均血流速度。结果以30例健康儿童为对照组,68例偏头痛患儿中有52例血流速增快,6例血流速减慢,5例双侧流速不对称,5例前、后循环血流速快慢不相同。结论偏头痛儿童存在着脑血管舒缩功能障碍,通过TCD对偏头痛儿童的脑血管血流速度的检测,有助于偏头痛的诊断、鉴别诊断、药物选择及疗效评价。

Objective To study the haemodynamic changes of intracranial vascular using Transcranial Doppler（TCD） during the onset of migraine 1analyze the feature of TCD, clinical manifestation and treatment outcome of children with migraine, and im- prove the understanding of the disease. Methods Intracranial vascular blood flow velocity of 30 normal healthy children was measured by TCD as control. Simuhaneously, and the data of 68 children with migraine during the onset was retrospective ana- lyzed. The results were restored in computer and analyzed by Doppler frequency spectrum. Mean velocity（Vm） was automatically analyzed due to velocity of systole and diastole period. Results Among the 68 children with migraine, the blood flow velocity of 52 cases increased ,6 cases decreased ,5 cases were bilateral asymmetrical,5 cases, which were increased and decreased in poste- rior circulation and in anterior circulation, were not the same, with 30 normal healthy children in control group. Conclusion Child migraine usually have brain vasomotion dysfunction. The blood flow velocity examination by TCD for children with migraine is beneficial for diagnosis, differential diagnosis, drug selection and efficacy assessment.